1. Use Optical Measurement of Subcutaneous Abnormal Tissue of Portable Non-invasive System Design Presenter: Bing-Soug Ho Adviser: Jenq-Ruey Horng Chairman : Hung-Chi Yang 1

2. OUTLINE INTRODUCTION MATERIALS AND METHODS RESULT FUTURE WORK REFERENCE 2

3. INTRODUCTION 3

4. 1,513 INTRODUCTION 4

5. Hospital have examination: ◦ Tissue sections ◦ X-ray ◦ MRI ◦ CT 5

6. Non-invasive design: ◦ Body’s HB and HBo2 of light absorption ◦ Hypodermal 2-3cm ◦ Fast measurement ◦ Cost down ◦ Small and portable INTRODUCTION 6

7. MATERIALS AND METHODS 7

8. 660 940 Fig.1 Infrared absorption spectrum NIR: 近紅外線 ( 700nm~ 2,000nm) Infrared absorption spectrum: 紅外線吸收光譜 8

9. MATERIALS AND METHODS Fig.2 diffraction & scattering 9

10. MATERIALS AND METHODS Fig.3 System architecture 10

11. LED660nm(Red) and LED940nm(white): MATERIALS AND METHODS 1.7cm LED660nm LED940nm Detector Fig.4 11

12. RESULT 12

13. New Entity RESULT Fig.6Fig.5 13

14. Measurement Entity RESULT Fig.7 14

15. FUTURE WORK Collect more Phantom data Indicate tumor direction 15

16. REFERENCE REFERENCE [1]. Department of Health, Executive Yuan, R.O.C.(TAIWAN) [2]. Zhao, Zhongyao, et al. "Handheld tumor scanner for breast cancer detection." (2006). [3]. http://www.bli.uci.edu/ntroi/pubs/pdf/si_recipe.pdf [4]. Lelia Adelina Paunescu ” TISSUE BLOOD FLOW AND OXYGEN CONSUMPTION MEASURED WITH NEAR-INFRARED FREQUENCY-DOMAIN SPECTROSCOPY” Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Biophysics and Computational Biology in the Graduate College of the University of Illinois at Urbana-Champaign, 2001 16