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12/2013 The Present Evolution of Liver Transplantation in Europe EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries - 155 institutions 118,441 transplantations.

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Presentation on theme: "12/2013 The Present Evolution of Liver Transplantation in Europe EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries - 155 institutions 118,441 transplantations."— Presentation transcript:

1 12/2013 The Present Evolution of Liver Transplantation in Europe EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries - 155 institutions 118,441 transplantations - 106,849 patients From May 1968 to December 2013 www.eltr.org

2 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

3 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

4 12/2013 EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries - 155 institutions 118,441 transplantations - 106,849 patients From May 1968 to December 2013 781 2441 4963 1526 1002 21279 15923 16487 557 829 14354 11 2447 1127 2272 2033 500178 20318 2748 1901 4214 16 72 42 229 47 162

5 12/2013 Evolution of 118,364 Liver Transplantations in Europe * The decrease is owed to the fact that some centers had a delay in the updating of their data to the current development of a new data reporting system, *

6 12/2013 Evolution of the number of Liver Transplantations reported to the ELTR

7 12/2013 Evolution of the number of Liver Transplantations by Center

8 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

9 12/2013 Evolution of Donor Age 05/1968 – 12/2013

10 12/2013 Gender and Age distribution of Liver Donors 01/1988 - 12/2013

11 12/2013 Graft Survival according to Donor Age in Europe 01/1988 - 12/2013

12 12/2013 Graft Survival according to Donor Age in Elective Liver Transplantation 01/1988 – 12/2013

13 12/2013 Graft Survival according to Donor Age in Urgent Liver Transplantation 01/1988 - 12/2013

14 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

15 12/2013 Age and Sex of Recipients 05/1968 – 12/2013

16 12/2013 Evolution of Recipient Age 05/1968 – 12/2013

17 12/2013 Patient Survival according to Recipient Age 01/1988 - 12/2013 p Log Rank = 0.0001

18 12/2013 Patient Survival according to Adult Recipient Age 01/1988 - 12/2013

19 12/2013 Proportion of Pediatric Transplantation by Country 01/1988 - 12/2013

20 12/2013 Primary Indication of Liver Transplantation in Pediatric Patients 05/1968 - 12/2013

21 12/2013 Survival according to Children Recipient Age 01/1988 - 12/2013 PatientGraft

22 12/2013 Survival of Children < 2 yrs according to the Main Indication in Europe 01/1988 - 12/2013

23 12/2013 Survival of Children >= 2 yrs according to the Main Indication in Europe 01/1988 - 12/2013

24 12/2013 Graft Survival according to Adult Recipient Age 01/1988 - 12/2013

25 12/2013 Primary Indications of Liver Transplantion in Elderly Patients (>= 60 Years) 01/1988 - 12/2013

26 12/2013 Survival of Elderly Recipients (>= 60 Years) according to the Main Indication in Europe 01/1988 - 12/2013

27 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

28 12/2013 * Others :Budd Chiari : 869 Benign liver tumors or Polycystic diseases : 1334 Parasitic diseases : 84 Other liver diseases : 2047 Primary Diseases leading to Liver Transplantion in Europe 01/1988 - 12/2013

29 12/2013 Primary Indications of Liver Transplantion in Europe 01/1988 - 12/2013

30 12/2013 Evolution of Primary Diseases leading to Liver Transplantation in Europe 05/1968 - 12/2013

31 12/2013 Primary Diseases leading to Liver Transplantion by Country 01/1988 - 12/2013

32 12/2013 Primary Diseases leading to Liver Transplantation in Adult Recipients 01/1988 - 12/2013

33 12/2013 Patient and Graft Survival following Liver Transplantation 05/1968 – 12/2013

34 12/2013 Patient Survival according to the Year of Liver Transplantation 05/1968 – 12/2013

35 12/2013 Patient Survival according to the Indication 01/1988 - 12/2013

36 12/2013 Patient Survival according to the 1st Indication 01/1988 – 12/2013

37 12/2013 Graft Survival according to the Urgency of Liver Transplantation in Europe 01/1988 - 12/2013

38 12/2013 Graft Survival according to ABO Compatibility in Elective Liver Transplantation 01/1988 - 12/2013

39 12/2013 Graft Survival according to ABO Compatibility in Urgent LT 01/1988 - 12/2013

40 12/2013 Liver Transplantation in Europe Indications of Cirrhosis 01/1988 - 12/2013

41 12/2013 Evolution of Indications for Cirrhosis in Europe

42 12/2013 Survival of Patients with Cirrhosis as the First Indication (1) 01/1988 - 12/2013

43 12/2013 Survival of Patients with Cirrhosis as the First Indication (2) 01/1988 - 12/2013

44 12/2013 Primary Indications of Liver Transplantation For Virus related Cirrhosis in Europe 01/1988 - 12/2013

45 12/2013 Survival of Patients with Virus related Cirrhosis as the First Indication 01/1988 - 12/2013

46 12/2013 Survival of Patients with Virus related Cirrhosis as the First Indication 01/1988 - 12/2013

47 12/2013 Survival of Patients with Virus related Cirrhosis as the First Indication 01/1988 - 12/2013

48 12/2013 Liver Transplantation in Europe Indications in Hepato-Biliary Cancers 01/1988 - 12/2013 Others:Hepatoblastoma: 261 Epithelioid hemangioendothelioma: 186 Angiosarcoma: 20

49 12/2013 Evolution of Indications for Hepato-Biliary Cancers in Europe 05/1968 - 12/2013

50 12/2013 Survival of Patients with Liver Cancer as the First Indication 01/1988 - 12/2013

51 12/2013 Survival of Patients with HCC with and without underlying Cirrhosis 01/1988 - 12/2013

52 12/2013 Primary Indications of Liver Transplantation In Patients with Acute Hepatic Failure 01/1988 - 12/2013

53 12/2013 Survival of Patients with Acute Hepatic Failure as the First Indication 01/1988 - 12/2013

54 12/2013 Primary Indications of Liver Transplantation in Patients with Cholestatic Diseases 01/1988 - 12/2013

55 12/2013 Survival of Patients with Cholestatic Diseases as the First Indication 01/1988 - 12/2013

56 12/2013 Primary Indications of Liver Transplantation in Patients with Metabolic Diseases 01/1988 - 12/2013

57 12/2013 Survival of Patients with Metabolic Diseases as the First Indication 01/1988 - 12/2013

58 12/2013 Indications of Liver Transplantation for Other liver diseases in Europe 05/1968 - 12/2013

59 12/2013 Survival of Patients with Other Liver Diseases as the First Indication 01/1988 - 12/2013

60 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

61 12/2013

62 Graft Survival in Liver Transplantation only vs Liver Combined to other Organ Transplantation 01/1988 - 12/2013

63 12/2013 Graft Survival according to the Site of Transplantation in Elective LT 01/1988 - 12/2013

64 12/2013 Type of Liver Graft in Europe according to the Date of Transplantation

65 12/2013 Graft Survival according to the Type of Graft 01/1988 - 12/2013

66 12/2013 Alternatives to the Use of the Full Size Cadaveric Liver Grafts in Europe

67 12/2013 Graft Survival according to the Type of Graft 01/1988 - 12/2013

68 12/2013 Graft Survival according to the Type of Graft in Elective LT 01/1988 - 12/2013

69 12/2013 Graft Survival according to the Type of Graft in Urgent LT 01/1988 - 12/2013

70 12/2013 Graft Survival according to the Cold Ischemic Time in UW Elective LT 01/1988 - 12/2013

71 12/2013 Graft Survival according to the Cold Ischemic Time in UW Urgent LT 01/1988 - 12/2013

72 12/2013 Auxiliary vs Non Auxiliary Graft Survival in Elective Liver Transplantation 01/1988 - 12/2013

73 12/2013 Auxiliary vs Non Auxiliary Graft Survival in Urgent Liver Transplantation 01/1988 - 12/2013

74 12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

75 12/2013 Liver Transplantation in Europe Mortality and Retransplantation 01/1988 - 12/2013

76 12/2013 Mortality and Retransplantation According to Recipient Age 01/1988 - 12/2013

77 12/2013 Mortality and Retransplantation According to the 1st Indication 01/1988 - 12/2013

78 12/2013 Graft Survival according to the Number of Liver Transplantations in Europe 01/1988 - 12/2013

79 12/2013 Graft Survival according to the number of the LT in Elective Cases 01/1988 - 12/2013

80 12/2013 Graft Survival according to the number of the LT in Urgent Cases 01/1988 - 12/2013

81 12/2013 Patient Survival according to the number of Liver Transplantations 01/1988 - 12/2013

82 12/2013 Patient Survival according to the number of LTs in Elective cases for the 1st LT 01/1988 - 12/2013

83 12/2013 Patient Survival according to the number of LTs in Urgent cases for the 1st LT 01/1988 – 12/2013

84 12/2013 Mortality following the 1st LT 01/1988 - 12/2013

85 12/2013 Causes of Retransplant following the 1st LT 01/1988 - 12/2013

86 12/2013 ELTR Coordination Committee René Adam, MD, PhD. Custodian Vincent Karam, PhD. Data Manager Valérie Delvart, MA. Biostatistician Anne-Marie Lammerant Secretary European Liver Transplant Registry Hôpital Paul Brousse Centre Hépatobiliaire 12 Avenue Paul Vaillant Couturier 94804 Villejuif, France Tel. +33 1 45 59 38 28 www,eltr.org

87 12/2013 the support of: The ELTR continue to evolve thanks to the participation of the 153 centers and to: the colaboration with:

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