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Pathology Lap Pictures and Explanation POD II BLOCK Abdullah Al Garni
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Prostate gland, nodular hyperplasia تــــضخــم غـــدة الـــبروســـتاتا ( الموثة )
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well-circumscribed nodules
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hyperplastic glands With two layers well-circumscribed nodules margin the stroma
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Breast, Fibroadenoma ســــرطــــان الثــــــدي
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fibroadenomanormal breast tissuewell-demarcated border
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Large irregularly shaped glandular spacesfibrous stroma
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columnar epithelium Delicate stroma
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Breast, Invasive ductal carcinoma ســـــرطان الـــــثدي
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duct-like spacesfibrous stroma
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duct-like spacesfibrous stroma
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Non-neoplastic ductsInvading tumor cells Fat Stroma
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Tumor cells
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Invasive malignant glands
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Invasive squamous cell carcinoma EXAMPLE: Bronchous ســـرطـــان القصبات الهوائية
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central areas of keratinization
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intercellular bridges the large hyperchromatic nuclei
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Lung, Metastatic Carcinoma ســـــرطان الـرئة
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The lung tissue has been replaced by large sheets of malignant cells The sheets is formed of pleomorphic cells with hyperchromatic nuclei There is also extensive necrosis The characteristic architecture of the residual normal lung can be seen.
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Lipoma
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mature white fat cellsThe nucleus
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Schwannoma
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The tumor shows a mixture of two growth patterns: -In the Antoni A pattern of growth, elongated cells with cytoplasmic processes are arranged in fascicles in areas of moderate to high cellularity with little stromal matrix. The nuclear palisading can be seen. - In the Antoni B pattern of growth, the tumor is less densely cellular with a loose meshwork of cells along with microcysts and myxoid changes. In both areas, the cytology of the individual cells is similar, with elongated cell shape and regular oval nuclei A A B B
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Black arrow: Antoni A ; blue arrow: Antoni B
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Bone, osteosarcoma ســـــرطان العـــظـــم
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Spicules of tumor bone malignant osteoblasts that have produced spicules of bone surrounded by osteoid matrix (( characteristic of osteosarcomas)) External information
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Mitosis
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eosinophilic osteoid
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Uterus, leiomyosarcoma ســـــرطان الــــرحم
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high cellularity
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High (N/C ratio) enlarged nuclei
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Heart, acute myocardial infarction احتشاء عضلة القلب
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coagulative necrosis (SCAR)
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neutrophils
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Coagulative necrosis Granulation tissue
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Myocardial infarct, old احتشاء عضلة القلب, كبار السن
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(SCAR) fibroblasts
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Pulmonary edema تورم الرئة
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Congested alveolar septa Intra-alveolar transudate
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