1. What is the current status of AIDS World Wide? Meagan Munson

4. What is AIDS H.I.V. H.I.V. A. I. D. S. A. I. D. S. Cell-mediated immunity Cell-mediated immunity Opportunistic infection Opportunistic infection

5. Tests CD4 cell count CD4 cell count Viral Load Viral Load

6. A Model of HIV

8. Transmission

9. Symptoms and Signs Beginning symptoms Beginning symptoms Fevers Fevers Weight loss Weight loss Swollen glands Swollen glands Progression of symptoms as CD4 cells diminish Progression of symptoms as CD4 cells diminish Herpes Herpes Tuberculosis Tuberculosis

13. History Co-discoverer Co-discoverer 1981 1981

14. Global Statistics

16. Global Demographics

18. U.S. Statistics White less than 2,000 White less than 2,000 Yellow 2,000-5,999 Yellow 2,000-5,999 Orange 6,000-16,000 Orange 6,000-16,000 Red 16,000 + Red 16,000 +

19. State by State U.S. 902,223 U.S. 902,223 Top 5 New York 162,446 New York 162,446 California 133,292 California 133,292 Florida 94,725 Florida 94,725 Texas 62,983 Texas 62,983 New Jersey 46,703 New Jersey 46,703

20. Who? By Exposure Men who have sex with men 46% Men who have sex with men 46% Injection Drug use 25% Injection Drug use 25% Men who have sex with men and use injection drugs 25% Men who have sex with men and use injection drugs 25% Heterosexual contact 11% Heterosexual contact 11% Blood/ tissue transfusion Blood/ tissue transfusion Not reported 10% Not reported 10% By Sex Males 81.6 % Males 81.6 % Females 18.4% Females 18.4% By Race White 42.2% Black 40.6% Hispanic 15.9% Asian 0.8% American Indian 0.3% Unknown 0.2%

21. Treatment Nucleoside reverse transcriptase inhibitors Nucleoside reverse transcriptase inhibitors Nucleoside reverse transcriptase inhibitors Nucleoside reverse transcriptase inhibitors Zidovudine March 19, 1987 Zidovudine March 19, 1987 Didanosine October 9, 1991 Didanosine October 9, 1991 Emtricitabine August 2, 2004 Emtricitabine August 2, 2004 Non-Nucleoside reverse transcriptase inhibitors Non-Nucleoside reverse transcriptase inhibitors Non-Nucleoside reverse transcriptase inhibitors Non-Nucleoside reverse transcriptase inhibitors Nevirapine June 21, 1996 Nevirapine June 21, 1996 Efavirenz September 17, 1998 Efavirenz September 17, 1998 Protease inhibitors Protease inhibitors Protease inhibitors Protease inhibitors Tipranavir June 22, 2005 Tipranavir June 22, 2005 Atazanavir June 20, 2003 Atazanavir June 20, 2003

22. Treatment cont Entry inhibitors Entry inhibitors Entry inhibitors Entry inhibitors-Fuzeon Integrase inhibitors Integrase inhibitors Integrase inhibitors Integrase inhibitors Vaccine - Is it possible? Vaccine - Is it possible? Vaccine

23. NRTI’s and PI’s

24. AZT the first approved antiretroviral drug for treatment of HIV and AIDS the first approved antiretroviral drug for treatment of HIV and AIDS FDA approved March 1987 FDA approved March 1987

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26. Credits con’t Institute of Human Virology, “Dr. Gallo”. Photo. Institute of Human Virology. University of Maryland. 30 October 2005 http://www.ihv.org http://www.ihv.org UNAIDS, “Regional HIV and AIDS statitics”. Graph. December 2004. TheBody.com. World Health Organization. 15 October 2005 www.thebody.com www.thebody.com UNAIDS, “Global Summary”. Graph. December 2004. TheBody.com. World Health Organization. 15 October 2005 www.thebody.com www.thebody.com UNAIDS, “About 14,000…”. Graph. December 2004. TheBody.com. World Health Organization. 15 October 2005 www.thebody.com www.thebody.com Kaiser Family, “Cumulative numbers of AIDS cases”. Graph. December 2003. StateHelathFacts.org. Thebody.com 15 October 2005 Kaiser Family, “Cumulative numbers of AIDS cases”. Graph. December 2003. StateHelathFacts.org. Thebody.com 15 October 2005 Kaiser Family, “Cumulative numbers of AIDS cases by exposure”. Graph. December 2003. StateHelathFacts.org. Thebody.com 15 October 2005 Kaiser Family, “Cumulative numbers of AIDS cases by exposure”. Graph. December 2003. StateHelathFacts.org. Thebody.com 15 October 2005 U.S. Department of Health and Human Services, “Approved Mediacation to Treat HIV Infection”. September 2005. AIDSInfo. 13 October 2005 U.S. Department of Health and Human Services, “Approved Mediacation to Treat HIV Infection”. September 2005. AIDSInfo. 13 October 2005 Lonny Shavelson, “at rest”. Photo. Photowords.com. 30 October 2005 <www.photowords.com/aids