1.  Regulated by the ___________.  The original container must have a capital ___ and ___________________ indicating its schedule  A veterinarian must be registered with the DEA to purchase, dispense, or prescribe controlled substances.  Registration number must be on all controlled substance prescriptions and order forms.  Registration is valid for three years  Some states (Texas included) allows veterinarians without DEA numbers to administer or dispense controlled substances if they are employed by a registered veterinarian. However, they cannot purchase them or write a prescription for them.  C-I drugs cannot be prescribed to animals  C-II drugs must have written prescriptions and cannot be refilled  Controlled substances must be dispensed in child-proof containers that read “Caution: Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed.”

2.  Must be stored in a __________________ _________________ of substantial construction  Glass front, lightweight portable safes, and locked tackle boxes are not sufficient  Farm-call vehicles may have a steel toolbox attached to the vehicle  Log of ordering, receiving, and dispensing must be kept for ___ years (include stolen, spilled, lost)  Bound pages that are sequentially numbered  Write in ink  Take inventory every two years.  Computer records must not allow much editing

3.  Cytotoxic drugs- drugs that are poisonous to mammalian cells  Antineoplastic and antifungal agents  Could potentially be teratogenic or carcinogenic  _____________________/_____________________ agents- drugs that cause birth defects (not only in the patient, but also in the person dispensing the drug)  ___________________________ agents - drugs that cause cancer or preneoplastic changes  OSHA has guidelines for the safe use, storage, and disposal of these drugs

4.  Absorption through the skin when drug spills/drips  Inhalation of aerosolized drug when needle is removed from pressurized bottle, when dug is being crushed/broken, or when ampules are broken.  Ingestion of food contaminated with the drug  REMEMBER:  Store your lunch in a refrigerator that food is in!  Don‘t place lunch on a counter where meds are placed.  Wash your hands!  Every hazardous material should have a MSDS, package insert, and a hospital policy procedure sheet for spills and disposal of equipment.

5.  Store cytotoxic drugs separately from other drugs and clearly label them.  Prepare the drug just prior to administration in a low traffic, well-ventilated area.  Wear protective gear: mask (not surgical), gloves (multiple pairs if latex), gown with long sleeves and cuffs, goggles.  Use screw-on syringes and IV lines.  Recheck calculations.  Insure catheter placement is correct.  Place all equipment in sealable plastic bags immediately after use and into a leak and puncture proof hazardous waste container.  Clean up properly after use. Do not allow maintenance staff to handle cleaning  Chemotherapy spill kits are available

6. DDEFINITION: _________________________________________________________ ________________________________________________________________________ EExamples: FFlavoring to improve palatability FFormulating drugs into different forms to ease administration NNOTE: Diluting drugs with saline, crushing a tablet into a liquid, and mixing drugs together in a syringe or vial are all examples of compounding.

7.  Must be made and dispensed by a veterinarian or pharmacist  Unacceptable if causes drug residues in food animals or puts the general public at risk  Cannot be made for anyone outside the practice  A valid client patient relationship must exist  The compounded drug must meet safety and efficacy standards  Records must be maintained  Drug must be labelled correctly