1. Flow Diagram of the Main HOPE Trial and the HOPE-TOO Trial Extension The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

2. Baseline Characteristics of All HOPE Study Patients and of the Patients at Centers Continuing in the Trial Extension (HOPE-TOO) The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

3. Incidence and Relative Risks of Cancers and Deaths Due to Cancer The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

4. Kaplan-Meier Analysis of the Effects of Vitamin E on Incident Cancer and Major Cardiovascular Events for All 9541 Study Patients The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

5. Incidence and Relative Risks of Site-Specific Cancers The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

6. Incidence and Relative Risks of Major Vascular Events, Deaths, and Secondary Cardiovascular Outcomes The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

7. Kaplan-Meier Analysis of the Effects of Vitamin E on All Heart Failure Events and Hospital Admissions for Heart Failure in HOPE and HOPE-TOO Patients The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347

8. Lung Cancer in Large Randomized Trials of Vitamin E The HOPE and HOPE-TOO Trial Investigators JAMA. 2005;293:1338- 1347