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Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers Jiancheng Hu, Edward C. Stites, Haiyang Yu, Elizabeth A. Germino, Hiruy S. Meharena,

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Presentation on theme: "Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers Jiancheng Hu, Edward C. Stites, Haiyang Yu, Elizabeth A. Germino, Hiruy S. Meharena,"— Presentation transcript:

1 Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers Jiancheng Hu, Edward C. Stites, Haiyang Yu, Elizabeth A. Germino, Hiruy S. Meharena, Philip J.S. Stork, Alexandr P. Kornev, Susan S. Taylor, Andrey S. Shaw Cell Volume 154, Issue 5, Pages 1036-1046 (August 2013) DOI: 10.1016/j.cell.2013.07.046 Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

3 Figure 2 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

4 Figure 3 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

5 Figure 4 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

6 Figure 5 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

7 Figure 6 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

8 Figure S1 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

9 Figure S2 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

10 Figure S3 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

11 Figure S4 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

12 Figure S5 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

13 Figure S6 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

14 Cell 2013 154, 1036-1046DOI: (10.1016/j.cell.2013.07.046) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

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