1. Poliovirus By: Ben Strozyk

2. Poliovirus  Causes poliomyelitis (aka polio) or infantile paralysis

3. Discovery  In 1909 by Karl Landsteiner and Erwin Popper (his assistant)

4. Type of Genetic Material  Positive-sense single-stranded RNA  From the enterovirus family  spreads quickly and attacks nervous system

5. Specific Structural Information  Only has a non-enveloped icosahedral protein coat

6. Types of Polio  Subclinical poliomyelitis (95% of all cases)  General discomfort or uneasiness (malaise)  Headache  Red throat  Slight fever  Sore throat  Vomiting

7. Types of Polio  Paralytic Poliomyelitis  Fever (early)  Constipation  Breathing/ Swallowing difficulty  Muscle spasms (calf, neck, or back)  Muscle pain  Muscle weakness

8. Transmission  Direct human to human contact  Infected feces or mucus/phlegm

9. Polio Incidences  Cases in U. S.  1952 - 60,000 cases and 3,000 deaths (peak)

10. People Affected by Polio  The greatest risk of contracting it is in India and Western/Central Africa

11. Mostly likely to Effect….  Children, pregnant women, and the elderly  In the summer and in the fall when fall arrives

12. Vaccines  inactivated poliovaccine (IPV)  Created by Jonas Salk (1952)  oral polio vaccine (OPV)  Created by Albert Sabin (1957)  weakened virus  90% effective overall

13. Sources  http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002375/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002375/  http://www.ehow.com/facts_5031409_type-virus- polio.html http://www.ehow.com/facts_5031409_type-virus- polio.html  http://en.wikipedia.org/wiki/Poliovirus http://en.wikipedia.org/wiki/Poliovirus  http://www.dhpe.org/infect/polio.html http://www.dhpe.org/infect/polio.html