1. Objective: Understand the process of Translation
Key Words: translation, codon, anticodon, mRNA
Replication
DNA
Transcription
mRNA
Translation
Protein

2. What molecule is produced? How do nitrogen bases pair?
Objective: Compare and Contrast Replication, Transcription and Translation
Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
Do Now:
Transcription and Translation are two processes involved in protein synthesis.
Compare and contrast Replication, Transcription and Translation.
For each process explain:
Where does it occur?
What is the goal?
Which molecules and organelles play a role in Translation involved?
What molecule is produced?
How do nitrogen bases pair?
Process
Where it happens?
What is the goal?
Which molecules/
organelles play a role?
What molecule is produced?
How do nitrogen bases pair?
Replication
Transcription
Translation
A – T
T – A
C – G
G - C
DNA
Helicase
DNA polymerase
Ligase
Nucleus
Make two identical
copies of DNA
DNA
A – U
T – A
C – G
G - C
Copy information
from DNA to mRNA
DNA
mRNA
RNA polymerase
Nucleus
mRNA
Ribosome
mRNA
tRNA
Amino-acids
A – U
U – A
C – G
G - C
Ribosomes in
cytoplasm or ER
Proteins or
Polypeptides
Synthesis of
proteins

3. Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
Objective: Compare and Contrast Replication, Transcription and Translation
Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
REPLICATION
In replication:
Cytosine pairs to _____________
Guanine pairs to _____________
Adenine pairs to _____________
Thymine pairs to ____________
Write the nitrogen base sequence of the complementary DNA strand
DNA molecule:
Guanine
Cytosine
Thymine
Adenine T A C G
A T G G G T T C A C C A A G C T G T G A A T T T A C G T A G A T G C
T A C C C A A G T G G T T C G A C A C T T A A A T G C A T C

4. Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
Objective: Compare and Contrast Replication, Transcription and Translation
Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
TRANSCRIPTION
In transcription:
Cytosine pairs to ________________________
Guanine pairs to ________________________
Adenine pairs to ________________________
Thymine pairs to ________________________
Below, write the base sequence that would appear on an mRNA strand after transcription of upper DNA strand.
mRNA : __________________________________________________________________
Guanine
Cytosine
Uracil
Adenine
A U G G G U U C A C C A A G C U G U G A A U U U A C G U A G T A C G
A U G G G U U C A C C A A G C U G U G A A U U U A C G U A G

5. Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
Objective: Compare and Contrast Replication, Transcription and Translation
Key Words: translation, codon, anticodon, mRNA, bases, polypeptide
TRANSLATION
Use the Genetic Code to determine the order of amino acids in the resulting protein fragment.
Protein:
Met – Gly – Ser – Pro –Ser – Cys – Glu – Phe –Thr Stop

6. Do Now:
Animal cells utilize many different proteins. Discuss the synthesis of proteins in an animal cell. Your answer must include at least: (3)
(1) the identity of the building blocks required to synthesize these proteins
(2) the identity of the sites in the cell where the proteins are assembled
(3) an explanation of the role of DNA in the process of making proteins in the cell