1. Mitosis Biology 1114

2. Definitions Asexual ReproductionInterphase AstersKaryotype Cell PlateKinetochore CentriolesMeiosis CentromereMetaphase ChromatidMitosis ChromatinPloidy ChromosomesProphase DiploisS Phase G1 PhaseSpindle Fibers G2 PhaseSporophyte GameteSynapsis CametophyteTelophase HaploidZygote

3. Two Types of Life Forms Unicellular 1. The Invisible World 2. Original Life 3. Found Everywhere 4. Photosynthesis and Decomposition 5. Potentially Immortal Multicellular 1. Communal 2. Growth and Division Necessary

4. Cell Growth and Division Uses Process of Mitosis Allows for Growth from Infant to Adult Necessary to Replace Worn Tissues Necessary for Generating New Cells Note: Somatic Cells reproduce by mitosis. Sex Cells reproduce by meiosis.

5. Prokaryotic Cells are Much Simpler in their Organization than are Eukaryotes

6. Simple Prokaryotic Reproduction 1.Replicates 2.Attaches 3.Separates

7. Creates Genetic Equals Advantage is that all cells are genetic equals. Disadvantage is that all cells are genetic equals. Binary Fission is Simple Cloning

8. Celebrity Sheep Has Died at Age 6 Dolly, the first mammal to be cloned from adult DNA, was put down by lethal injection Feb. 14, 2003. Prior to her death, Dolly had been suffering from lung cancer and crippling arthritis. Although most Finn Dorset sheep live to be 11 to 12 years of age, postmortem examination of Dolly seemed to indicate that, other than her cancer and arthritis, she appeared to be quite normal. The unnamed sheep from which Dolly was cloned had died several years prior to her creation. Dolly was a mother to six lambs, bred the old-fashioned way.

9. Eukaryotic Cell Divison and Chromatin DNA and Histone Protein Complex Dispersed in the Nucleus Has Ability to Condense

10. Chromosomes When Chromatin Condenses During Cell Divison It is Referred to as Chromosomes

12. Human Chromosomes

13. Human Karyotype

14. Mitosis A process of forming generally similar daughter cells by replicating and dividing the original chromosomes. Cellular division used by simple organisms. The sequence of DNA replication, growth and cell division that cells go through.

16. Interphase No Division Occurring Metabolically Active Nucleolus Visible DNA and Organelles Duplicating Nucleus is Intact 90% of Cell’s Time is Spent in Interphase

18. Prophase Nucleolus Disappears Centrioles Move to Poles Spindle Fibers Form Chromosomes Visible Nuclear Membrane Disappears

19. Metaphase Shortest Phase Chromosomes Line up in Middle of Cell

20. Anaphase Chromosomes Separate into Separate Chromatids Begin to Move to Opposite Ends of the Cell

21. Telophase Chromosomes Arrive at Poles Disappear into Chromatin Spindles Disappear Nuclear Membrane Reappears Nucleolus Reappears

29. Review

30. Identify the Following Stage of Mitosis

35. Cancer results when normal body cells grow out of control without regulation. They can invade other tissues causing enough damage to kill the host.

37. Control of Mitosis and Cancer 6.5 Million Cases of cancer in USA Yearly Not all Cancers are Lethal Tumor = Mass of Cancer Cells Benign = Remain Localized Malignant = Escape Site and Spreading Metastasis = Spreading Treatment = Radiation and Chemotherapy

38. Metastasis

39. Basal Cell Carcinoma Non-melanoma skin cancers are far more common but less dangerous than malignant melanoma and rarely fatal. Basal cell carcinoma and squamous cell carcinoma frequently appear on sun-exposed skin after many years of exposure. This exposure also causes premature ageing of the skin. Non- malignant skin cancers are easily treated by minor surgery. If left, non-melanoma skin cancers will grow and disfigure - therefore early treatment is recommended.

40. Skin Cancer Malignant melanoma is the rarest, but most serious form. It affects the pigment-producing cells (melanocytes) found in the skin and can appear as a new mole, or arise from an existing mole on the skin. Malignant melanoma has the potential to spread to other sites or organs within the body but is CURABLE if treated early.

41. Sunshine is the single most important causative factor in all skin cancers.

42. Skin Cancer

47. Tobacco is a Carcinogen

48. Oral Cancer Associated with Tobacco Use

50. Cigarette smokers, depending on the number of cigarettes smoked have a six- fold increase of dying from oral and pharyngial cancer as a non-smoker Health Canada

51. Systemic Tumors

56. Cancer of the Kidney

57. Brain Cancer