1. HIV and Human Evolution Activity

2. Right now HIV is passed through - blood, and sexual fluids So only activities like IV drug use or unprotected sexual contact will make you susceptible But what if that changes? …airborne?

3. HIV theories had tobe We have always known that due to evolution, and probability, there had to be people out there that were resistant to HIV …so we found them. How could we have found them…. Nothing is ever 100%.... Like paternity

4. CCR5 delta 32 Is a mutation where a section of a gene, is deleted Chromosome 3- position 21, short arm

5. How did we find people that have a genetic mutation that makes them resistant to HIV?

6. HIV- transmitted through bodily fluids (High risk behavior) Let’s say… HIV becomes airborne…. Who lives and who’s a goner? CCR5- 1 copy (slow progression) CCR5/ CCR5- 2 copies resistant…

9. Draw 4 punnett squares in your notebook Greater than 50% resistant and your descendents live….

10. 5-14% of Northern Europeans Study done tested 4,166 genotypes  0% Amer. Indian, African, East Asian Rare in African descended or Asian descended populations CCR5/ x = 2 years before you really get sick CCR5/ CCR5= resistant to AIDS

11. Northern Europe as defined by the United Nations (marked blue):United Nations

12. Northern Europe is the northern part or region of Europe. The United Nations defines Northern Europe as including the following countries and dependent regions:[1][2]northernregionEuropeUnited Nations[1][2] Denmark Denmark  Faroe Islands Faroe Islands Estonia Estonia Finland Finland  Åland Islands Åland Islands Iceland Iceland Ireland Ireland Latvia Latvia Lithuania Lithuania Norway Norway  Svalbard and Jan Mayen SvalbardJan Mayen Sweden Sweden United Kingdom United Kingdom  Isle of Man Isle of Man  Channel Islands: Guernsey and Jersey Channel Islands Guernsey Jersey