1. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Update – September 2009 Co-Chairs – Stephen Capar and Jo Marie Cook

2. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Meeting Agenda Report from Official Methods Board Subgroup Reports Pesticides Veterinary Drugs Metals Unknowns SLV Protocols Methods for Review New Topics – Discussion

3. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Meeting Business Open Forum – What are your needs? Call for Leaders Nominations Elections Break into Subgroups

4. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Challenges Networking Reaching Consensus Developing Best Methods Establishing Validation Criteria Completing Validation Publishing Work

5. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES International Membership 577 Stakeholders 179 Applications 22 Counties (56% USA, 16% Canada) (Argentina, Belgium, Brazil, Chile, China, France, Germany, Holland, Hong Kong, India, Ireland, Italy, Japan, Kenya, Korea, Sweden, Switzerland, Thailand, The Netherlands, United Kingdom)

6. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Balanced Participation 30 - Industry 1 - Trade Organization 23 - Laboratory, Private 26 - Laboratory, Govt, U.S. Federal 29 - Laboratory, Govt, State 51 - Laboratory, Govt, non U.S. 7 - Academia

7. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Subgroups Pesticides (compare QuEChERS-like) Veterinary Drugs (seafood) Metals (ceramics ring test) Unknowns (“toolbox” for adulerants )

8. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Other Needs Emerging Organic Pollutants Food Contact Migrants Colors and Dyes QA and Validation Criteria Other Food Issues: composition, nutrients, allergens, filth…

9. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Emerging Organic Pollutants & Food Contact Contaminants Bisphenol A in baby bottles Benzene in soft drinks Phthalates, other plasticizers Vinyl Acetate in chewing gum Perchlorate in water and lettuce Acrylamide in fried foods Perfluorooctanesulfonic acid in pizza boxes Nanomaterials in Packaging & Foods

10. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Colors & Dyes Sunset yellow (E110) Quinoline yellow (E104) Carmoisine (E122) Allure Red (E129) Tartrazine (E102) Ponceu 4R (e124)

11. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES 2009 Priorities Melamine Protein Authenticity Vet Drugs in Seafood Metals Speciation & Ceramics Single Lab Validation Protocols

12. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Compare Melamine Methods Compounds screened Compounds found Incurred residue recoveries Matrices Test Kits Action Limits

13. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Protein Quality Control Support Label Claims Detecting Economic Adulteration Detecting Contamination Ingredients vs Finished Product Instrumental vs Test Kits Methods for today’s needs!

14. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Protein Quality Control Support Label Claims Detecting Economic Adulteration Detecting Contamination Ingredients vs Finished Product Instrumental vs Test Kits Methods for today’s needs!

15. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Protein Meetings U.S. Pharmacopeia Food Protein Workshop Developing a Toolbox of Analytical Solutions to Address Adulteration June 16 – 17, 2009 USP Headquarters, Rockville, Maryland http://www.usp.org/meetings/workshops/foodProteinWorkshop2009.html http://www.usp.org/meetings/workshops/foodProteinWorkshop2009.html Economically Motivated Adulteration in Protein and Pharmaceuticals The FDA is inviting attendees to register for the EMA May 1st meeting at http://www.fda.gov/oc/meetings/ema.html http://www.fda.gov/oc/meetings/ema.html

16. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Seafood Issues Veterinary Drugs Species identification Metals &Toxic Elements Pesticides Pathogens Environmental Conditions Good Aquaculture Practices

17. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Metals 42 members Arsenic, Cadmium, Lead, Mercury Arsenic Speciation SLV for Metals Pb & Cd Ceramics Proficiency Swedish National Food Administration, http://www.slv.se http://www.slv.se ISO 6486-1/EN 1388-1 method, ceramic cup and solution

18. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES SLV Protocols Pesticides Veterinary Drugs Metals Compare varieties of QuEChERS Qualitative MS Screens

19. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES SLV Protocols Harmonized Procedures Harmonized Performance Criteria EU Commission Decision 96/23/EC IUPAC Harmonized Guidelines Inter-Laboratory Data Sharing ISO 17025

20. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Multi-Residue Issues Representative Analytes, Matrices Method Extensions Method Modifications Range, AL’s, LOQ’s, LODs Instrument Equivalency Sharing Ruggedness Sharing Stability Sharing Data with Different Methods

21. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES Multi-Residue Issues Objectivity / Bias Sampling / Test Portions Extraction Efficiency Processing Losses Analyte Stability Homogeneity Uncertainty System Suitability

22. Chemical Contaminants & Residues in Food Community BRINGING SCIENTISTS AND INDUSTRY TOGETHER TO DEVELOP AND VALIDATE BETTER METHODOLOGIES www.flworkshop.com\community-1st.html