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Copyright © 2009 Pearson Education, Inc. Genomics, Bioinformatics, and Proteomics Chapter 21 Lecture Concepts of Genetics Tenth Edition
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Copyright © 2009 Pearson Education, Inc. 21.1Whole-Genome Shotgun Sequencing Is a Widely Used Method for Sequencing and Assembling Entire Genomes
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Copyright © 2009 Pearson Education, Inc. Figure 21.1
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Copyright © 2009 Pearson Education, Inc. 21.1Whole-Genome Shotgun Sequencing Is a Widely Used Method for Sequencing and Assembling Entire Genomes 21.1.1High-Throughput Sequencing
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Copyright © 2009 Pearson Education, Inc. Figure 21.2
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Copyright © 2009 Pearson Education, Inc. 21.1Whole-Genome Shotgun Sequencing Is a Widely Used Method for Sequencing and Assembling Entire Genomes 21.1.2The Clone-by-Clone Approach 21.1.3Draft Sequences and Checking for Errors
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Copyright © 2009 Pearson Education, Inc. Figure 21.3
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Copyright © 2009 Pearson Education, Inc. 21.2DNA Sequence Analysis Relies on Bioinformatics Applications and Genome Databases 21.2.1Annotation to Identify Gene Sequences 21.2.2Hallmark Characteristics of a Gene Sequence Can Be Recognized During Annotation
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Copyright © 2009 Pearson Education, Inc. Figure 21.4
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Copyright © 2009 Pearson Education, Inc. Figure 21.5
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Copyright © 2009 Pearson Education, Inc. Figure 21.6a
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Copyright © 2009 Pearson Education, Inc. Figure 21.6b
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Copyright © 2009 Pearson Education, Inc. Figure 21.6c
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Copyright © 2009 Pearson Education, Inc. Figure 21.7
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Copyright © 2009 Pearson Education, Inc. 21.3Functional Genomics Attempts to Identify Potential Functions of Genes and Other Elements in a Genome 21.3.1Predicting Gene and Protein Functions by Sequence Analysis
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Copyright © 2009 Pearson Education, Inc. Figure 21.8
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Copyright © 2009 Pearson Education, Inc. Figure 21.9
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Copyright © 2009 Pearson Education, Inc. 21.3Functional Genomics Attempts to Identify Potential Functions of Genes and Other Elements in a Genome 21.3.2Predicting Function from Structural Analysis of Protein Domains and Motifs
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Copyright © 2009 Pearson Education, Inc. 21.4The Human Genome Project Revealed Many Important Aspects of Genome Organization in Humans 21.4.1Origins of the Project 21.4.2Major Features of the Human Genome
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Copyright © 2009 Pearson Education, Inc.
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© 2012 Pearson Education, Inc. Table 21.1
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© 2012 Pearson Education, Inc. Table 21.1
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Copyright © 2009 Pearson Education, Inc.
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Figure 21.11
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Copyright © 2009 Pearson Education, Inc. Figure 21.12a
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Copyright © 2009 Pearson Education, Inc. Figure 21.12b
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Copyright © 2009 Pearson Education, Inc. 21.5The “Omics” Revolution Has Created a New Era of Biological Research Methods
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© 2012 Pearson Education, Inc. Figure 21.13
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© 2012 Pearson Education, Inc. Personal Genomics The Human Microbiome Project No Genome Left Behind— 10K genomes in 5 years
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Copyright © 2009 Pearson Education, Inc. 21.6Comparative Genomics Analyzes and Compares Genomes from Different Organisms
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Copyright © 2009 Pearson Education, Inc. Table 21.2
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Copyright © 2009 Pearson Education, Inc. Table 21.3
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Copyright © 2009 Pearson Education, Inc. Figure 21.12
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© 2012 Pearson Education, Inc. Table 21.3
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Copyright © 2009 Pearson Education, Inc. Figure 20-8 Copyright © 2006 Pearson Prentice Hall, Inc.
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Copyright © 2009 Pearson Education, Inc. Figure 21.15
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Copyright © 2009 Pearson Education, Inc. Table 21.4
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Copyright © 2009 Pearson Education, Inc. 21.6Comparative Genomics Analyzes and Compares Genomes from Different Organisms The Rhesus Monkey Genome The Sea Urchin Genome The Neanderthal Genome Evolution of Multigene Families
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Copyright © 2009 Pearson Education, Inc. Figure 21.16
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Copyright © 2009 Pearson Education, Inc. Figure 21.17
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Copyright © 2009 Pearson Education, Inc. Figure 21.18
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Copyright © 2009 Pearson Education, Inc. 21.8Transcriptome Analysis Reveals Profiles of Expressed Genes in Cells and Tissues
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Copyright © 2009 Pearson Education, Inc. Figure 21.21
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Copyright © 2009 Pearson Education, Inc. Figure 21.22
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Copyright © 2009 Pearson Education, Inc. Figure 21.22a
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Copyright © 2009 Pearson Education, Inc. Figure 21.22b
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Copyright © 2009 Pearson Education, Inc. 21.9Proteomics Identifies and Analyzes the Protein Composition of Cells Reconciling the Number of Genes and the Number of Proteins Expressed by a Cell or Tissue Proteomics Technologies: Two-Dimensional Gel Electrophoresis for Separating Proteins
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Copyright © 2009 Pearson Education, Inc. Figure 21.24
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Copyright © 2009 Pearson Education, Inc. Figure 21.25
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Copyright © 2009 Pearson Education, Inc. 21.9Proteomics Identifies and Analyzes the Protein Composition of Cells Proteomics Technologies: Mass Spectrometry for Protein Identification
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Copyright © 2009 Pearson Education, Inc. Figure 21.26
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Copyright © 2009 Pearson Education, Inc. Figure 21.27
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Copyright © 2009 Pearson Education, Inc. 21.10Systems Biology Is an Integrated Approach to Studying Interactions of All Components of an Organism’s Cells
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© 2012 Pearson Education, Inc. Figure 21.29
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