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Published byClaire Douglas Modified over 9 years ago
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DNA Nanotubes: Construction and Characterization of Filaments Composed of TX-tile Lattice
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Material: Triple-crossover (TAO) tiles modified with thiol-containing dsDNA stems projected out of the tile plane Analytical tools: TEM, AFM Key: Sticky-end programmable (“smart glue”) –Properly designed sets of DNA oligonucleotides are able to self-assemble into complex, highly organized structures. Applications –Scaffolds for the creation for the creaction of nanoelectic circuits and other desired objects requiring nanometer scale feature resolution
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Interesting filamentous structures The length scale of DNA nanotubes Experimental results –1. Reaction of thiolated DNA with nanogold –2. Reaction of DNA containing free amine with Modified nanogold –3. DNA nanotube formation via disulfide and polysulfide structures between tiles
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