1. Human Anatomy and Physiology Lymphatic system

2. Components 1. Lymphatic vessels ‘Mop up’ fluid escaped from vasculature

3. Lymphatic vessels A one-way system to the heart Absent in bones, teeth, CNS

4. Lymphatic vessels Structure Minivalves and collagen fibers Valve opens when interstitial pressure rises

5. Lymphatic vessels Structure Proteins, fat travel via lymph (lacteals) Cancer travels via lymph Lymph nodes (macrophages, lymphocytes) Slow circulation depends on muscle contraction and action of respiration

6. Components 2. Lymphatics cells and tissue House phagocytic cells (cells that engulf) and lymphocytes (T and B cells) used in defense Tissue composed mostly of reticular CT

7. Lymph organs

8. 1. Lymph nodes Macrophages in nodes destroy microorganisms Contain lymphocytes that destroy antigens 2. Spleen Provides for lymphocyte proliferation and immune surveillance because it filters blood 3. Thymus Causes T lymphocytes to become immunocompetent

9. Lymph organs 4. Tonsils Bacteria enter blind-ending sacs of tonsils and through epithelium into lymphoid tissue to be destroyed 5. Peyer’s patches Destroy bacteria in large numbers on intestine wall and appendix prior to breaching intestinal wall