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BIO 1110 1
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Tissues: A group of similar cells, having a similar origin, and functioning together to carry out specialized activities. Tissues can be solid, semi-solid or liquid. From conception until approximately day 14, all cells look and function the same (undifferentiated=stem cells). Around day 15 post conception, cells start to differentiate or take on new characteristics. This is the start of tissue formation. 2
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Histology is the study of tissues. There are 4 main types of tissues in the human body: Epithelial Connective Muscular Nervous 3
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Tightly packed cells arranged in continuous single or multi-layered sheets. Characteristics: Avascular- without blood vessels. Epithelium gets nutrients from the adjacent connective tissue. Bottom surface of epithelium is attached to the basement membrane (fibers that act like glue) Has a nerve supply. 4
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This type of tissue is found on the outer covering of the skin and some internal organs as well as lining body cavities and some internal hollow organs. There are 9 different types of lining/covering epithelium. Epithelial tissue is classified based on the number of cell layers present and the shape of the cells of the tissue.
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Simple- - Single layer of tightly packed cells Stratified- - 2 or more layers of tightly packed cells 7
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Pseudostratified Looks like many layers because not all cells reach the surface and the nuclei lie at different levels 8
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Squamous Thin, flat and irregularly shaped Cuboidal Square/cube shaped Columnar taller than wide Transitional change shape due to stretching or movement of body parts 9
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A single layer of tightly packed thin, flat, irregularly shaped cells Location: Lines the blood vessels Forms the peritoneum, pericardium and pleural linings Found in the air sacs of lungs (alveoli) Function: Allows for easy diffusion of gases and blood components
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Simple Squamous – Top View – found in the walls of capillaries and alveoli of lungs
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A single layer of tightly packed cube shaped cells. Location: Lines kidney tubules, ducts of glands, and secreting parts of glands Function: Secretion (force materials out of the cells) and absorption (pull materials into the cells)
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Simple Cuboidal Epithelial Tissue – this is of ducts of the kidney
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A single layer of tightly packed rectangular cells Can be non-ciliated or ciliated (tiny hairs) Non-ciliated have microvilli (finger-like projections) on the free surface of the cells Non-ciliated Location: Lines the gastrointestinal tract (from stomach to anus) Non-ciliated Function: Secretion and absorption Microvilli increase surface area 200-300 times for absorption
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Ciliated Location: Lines tubes of the respiratory tract, fallopian tubes, and ventricles of the brain Ciliated Function: The cilia beat in unison to move substances outside the cell like mucus and egg cells.
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Simple Columnar Non-Ciliated Epithelial Tissue - This is a cross section through the small intestine – for absorption – microvilli on surface of cells
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23 A single layer of tightly packed columnar cells that appear to be multi-layered Location: Ciliated- Lines respiratory tract Non-ciliated- Male urethra Function: Ciliated- moves materials across the apical surface of a tissue. Non-ciliated- Absorb and protect
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Multiple layers of tightly packed squamous epithelial cells. Location: Areas that are subject to much “wear and tear”. ▪ Upper layers are designed to be shed and replaced. Function: Protection
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Two layers of cube shaped epithelial cells Rare Location: Lining the ducts of glands found in the esophagus Function: Moderate protection from the stomach acid that refluxes
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Multiple layers of columnar epithelial cells Rare Only the layer closest to the lumen (opening in a duct) is columnar in shape. The outer layers are somewhat squashed. Location: Lining the ducts of glands lining the esophagus Function: Moderate protection from stomach acid that refluxes
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Epithelial tissue that has a variable shape Can stretch and relax multiple times without being damaged Location: Lines the urinary bladder Function: Protection
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