1. Organic Chemistry An introduction to the chemicals of life!

2. Organic vs. Inorganic Contains Carbon Found in and/or produced by living things Includes fossil fuels Generally does not contain Carbon Natural and synthetic substances

3. Characteristics of Carbon: Can form 4 strong bonds May form double and triple bonds Strong bonds with many non- metals (H, O, Cl, N) Can form long chain molecules

4. We will begin with hydrocarbons Hydrocarbons contain only carbon and hydrogen There are three types of hydrocarbons: –Aliphatic –Alicyclic –Aromatic

5. ALIPHATIC HYDROCARBONS Aliphatic hydrocarbons contain chains of carbon atoms There can be as few as one carbon and as many as several thousand in these chains The chains can be “straight” or they can be branched

6. ALICYCLIC HYDROCARBONS Alicyclic hydrocarbons contain rings of carbon atoms There can be as few as three carbons in a ring or as many as 10-15 The ring systems are three dimensional, not flat

7. AROMATIC HYDROCARBONS Aromatic hydrocarbons usually contain six member carbon rings with alternating single and double bonds around the ring The system of single and double bonds makes them aromatic rather than alicyclic The basic ring member is called “benzene”

8. ORGANIC COMPOUNDS Organic compounds can be thought of as being made up of a small number of different parts which can be assembled in an infinite number of ways. The longest chain of an organic compound is considered the parent structure. The groups attached are called functional groups There are many more organic compounds than inorganic compounds

9. How are you doing so far? Organic chemistry is very important for anyone pursuing any type of medical career In college, organic chemistry is usually a two or three semester experience

10. SATURATED VERSUS UNSATURATED A saturated organic compound contains only carbon-carbon single bonds They can be aliphatic or alicyclic, but not aromatic An unsaturated organic compound contains at least one carbon-carbon double or triple bond They can be aliphatic, alicyclic, or aromatic

11. Back to the aliphatic hydrocarbons There are three types of aliphatic hydrocarbons –alkanes (single bonds only) –alkenes (at least one double bond) –alkynes (at least one triple bond)

12. ALKANES Also called the paraffins They are saturated hydrocarbons (contain maximum number of hydrogen atoms) Have the general formula, C n H 2n+2 Let’s consider the first thirty alkanes (handout chart)

13. If there is only one Carbon, how many hydrogen atoms are there? Answer = 4

14. CH 4 is called methane What about two carbon atoms?

15. Alkanes Chart - handout Let’s go to the the board and look at the structural formulas for the alkanes

16. MOLECULAR ISOMERS Molecular isomers have the same formula, but different structure –the difference occurs based on how the carbon atoms are arranged –there can be many different isomers for the same formula

17. Example Butane has a formula of C 4 H 10 C – C – C – C C – C – C | C

18. Let’s Go to the board again and write the 5 isomers for Hexane C 6 H 14

19. ALKENES Also called the olefins They are unsaturated hydrocarbons containing one or more carbon-carbon double bonds They are named by changing the -ane ending to -ene They have the general formula C N H 2N

20. ALKYNES Also called the acetylenes They are unsaturated hydrocarbons containing one or more carbon-carbon triple bond They are named by changing the -ane ending to -yne They have the general formula C N H 2N-2

21. ALKYL GROUPS (handout) Alkyl groups are functional groups made from the alkanes –they are saturated –to name them, change the -ane ending to -yl –example: methane becomes methyl

22. Naming organic compounds In order to name organic compounds, a very systematic approach is used The system is called IUPAC –International Union of Pure and Applied Chemistry

23. Rules for IUPAC naming Determine the parent structure (longest continuous carbon chain) and write down the name Circle each substituent group (functional group) attached to the parent structure Number the parent structure starting from the end closest to a substituent group

24. More IUPAC rules Write down the name of each substituent group preceded by a number showing the point of attachment to the parent structure Use commas to separate numbers and hyphens to separate substituent groups Use binary prefixes to indicate how many of each substituent group is present

25. Binary Prefixes 2 Di 3Tri 4Tetra 5Penta 6Hexa 7Hepta 8Octa 9Nona 10Deca