1. Advances in Stem Cell Therapy Karim Nayernia Professor of Human Genetics & Stem Cell Biology

2. Stem cells: Balance between proliferation and differentiation

3. Stem cells: Developmental origin

4. Proliferation versus Differentiation

5. Therapeutical purposes: cell-based therapy, gene therapy new approaches for the treatment of cardiovascular, neurodegenerative and musculoskeletal diseases, as well as diabetes and cancer Understanding about the early development Understanding about pathophysiology of diseases Cell-based phenotypic and pathway-specific screens of chemicals Stem Cell Application

6. Sources of Stem Cells (I)

7. Sources of Stem Cells (II): iPS Cells

8. Adult vs. Embryonic Stem cells

9. How to make an organ, tissue engineering Limited cell availability Immunological rejection Control of stem cell fate, directed differentiation Policy issues Ethical issues Social issues Legal issues Problems to be overcome

10. Stem Cell Therapy Stem Cell isolation and culture (AD-MSC) Tissue Engineering Animal Models