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Osteoconductive phosphoserine-modified poly(ε-lysine) dendrons: synthesis, titanium oxide surface functionalization and response of osteoblast-like cell.

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Presentation on theme: "Osteoconductive phosphoserine-modified poly(ε-lysine) dendrons: synthesis, titanium oxide surface functionalization and response of osteoblast-like cell."— Presentation transcript:

1 Osteoconductive phosphoserine-modified poly(ε-lysine) dendrons: synthesis, titanium oxide surface functionalization and response of osteoblast-like cell lines by S. T. Meikle, G. Bianchi, G. Olivier, and M. Santin Interface Volume 10(79):20120765 February 6, 2013 ©2013 by The Royal Society

2 Physico-chemical characterization of G3 PL-PS dendrons. S. T. Meikle et al. J. R. Soc. Interface 2013;10:20120765 ©2013 by The Royal Society

3 Scanning electron microscopy of (a) unmodified etched TiO2 surfaces and (b) G3 PL-PS- functionalized TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10:20120765 ©2013 by The Royal Society

4 Surface analysis of TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10:20120765 ©2013 by The Royal Society

5 MG-63 osteoblast-like cell adhesion after 3 h incubation on (a) tissue culture plastic, (b) unmodified etched TiO2 and (c) PL-PS-functionalized TiO2. S. T. Meikle et al. J. R. Soc. Interface 2013;10:20120765 ©2013 by The Royal Society

6 Osteoblast-like cell proliferation on unmodified etched TiO2 and PL-PS-functionalized TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10:20120765 ©2013 by The Royal Society

7 SAOS-2 osteoblast-like cell differentiation on unmodified etched TiO2 and PL-PS-functionalized TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10:20120765 ©2013 by The Royal Society


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