1. LO: SWBAT explain how DNA replicates DN: h/0 DNA regents questions HW: read pp295-299 Castle Learning

2. DNA Replication (Hint) To make a copy What does REPLICATE mean?

3. What do we get when DNA replicates? DNA Replication + Two New DNA Molecules

4. DNA Structure Review What is DNA composed of? Nucleotides 4 types Adenine Thymine Guanine Cytosine Deoxyribose

5. How do the Bases Pair Up? All Teachers Go Crazy H Bonds

6. DNA Structure What shape is this? Double-Helix What scientists shared the Nobel Prize for their work on DNA? Maurice Wilkins Watson & Crick Rosalind Franklin

7. What Process is Taking Place Here? Cell Division Why do our cells need to divide? GROWTH REPAIR

8. What does the DNA do before a cell divides? Genetic Information (DNA) DNA must replicate before a cell divides Why must DNA replicate itself? DNA is the “Blueprint” for all cell activities. Each cell needs the entire “Blueprint” to function properly.

9. Steps of DNA Replication G - C C - G T - A A - T T - A DNA Molecule Bonds Broken G C C G T A A T T A 2 Separate Strands Step 1: Bonds between the bases are broken and the DNA Molecule is “Unzipped” Enzymes

10. Step 2: Individual bases find their “match” on each single strand of DNA. G C C G T A A T T A 2 Separate Strands Base Pairing GCTATGCTAT C G A T A CGATACGATA G C T A T Each strand is a Template for base pairing Enzymes DNA Polymerase

11. Step 3: Bonds between the bases are formed G C C G T A A T T A Bonds Formed G - C C - G T - A A - T T - A

12. DNA Replication G - C C - G T - A A - T T - A DNA Molecule G C C G T A A T T A 2 Separate Strands G - C C - G T - A A - T T - A Bonds Broken Base Pairing What is formed? 2 Identical DNA Molecules

13. What Process is this? DNA Replication Each strand serves as a Template

14. Summary Questions 1)Do you think DNA Replication is an accurate process? Why? 2)What do you think would happen if DNA did not accurately replicate? 3)What are some of the consequences? 4)DNA Replication AnimationDNA Replication Animation