1. DNA Structure How the structure of DNA was discovered and how it relates to its function of REPLICATION

2. How did we determine DNA’s structure? Will our model change?

4. Vocabulary O Be able to identify a nucleotide O Identify the molecules that make up rungs and sides of the double helix. O Explain the term antiparallel O Identify the 3’ and 5’ ends O Identify the two functions of DNA and how its structure relates.

5. How did experimental evidence determine the structure and function of DNA? O 5 Famouns DNA Experiments: O Griffith/Avery O Hershey/Chase O Chargaff O Watson/Crick/Franklin O Messelson/Stahl O Identify their experimental design and analysis! O Hypothesis…Methods…Data Analysis…Conclusion!

6. Griffith & Avery

7. Hershey and Chase

8. Chargaff

9. Watson/Crick/Franklin/Wilkins

10. Messelson and Stahl

11. DNA Replication…Animation Preview O DNA replication is a highly organized biological process. O In what sequence does the process occur? O What enzymes and molecules are involved in the process? O Distinguish between the leading and lagging strand? O Why must proofreading be an essential component of DNA replication?

12. Help Mrs. Krajewski’s chromosome replicate its DNA!!!

13. How is a chromosome related to DNA?