1. Hirnoberfläche Linsen system ~ 5 mm ~ 70 mm ~ 5 mm MR 10 m Bruno Weber, Nov 2004 Computer CCD 150 mm Kamera Elektronik Licht Einkopplung

2. MROI Project: Lens system Bruno Weber, Nov 2004

3. Concurrent Imaging Parameters fMRI signals:BOLD, (...) Optical signals:autofluorescence imaging (AF):oxidative metabolism laser speckle imaging (LSI):relative CBF intrinsic optical imaging (IOS):blood oxygenation fluorochrome-detection in the course of the development of smart MRI contrast agents Resolution:temporal >10 Hz spatial 10  m pixel size Penetration depth: LSI up to 1 mm AF/IOSless Electrophysiologysystem can/should be adapted at a later stage (?) Bruno Weber, Nov 2004 MROI Project

4. MROI Project new (tandem lens) Estimated maximal Costs GRIN lens test I€ 2‘000.- Lens system and light coupling, system development€ 12‘000.- Lens system, laser, light coupling, manufacturing€ 12‘000.- Polychrome V Monochromator€ 15‘000.- CCD Camera PCO Imaging, D-Kelheim€ 4‘000.- Standard Linux PC with 2 GB RAM€ 2‘000.- National Instruments D/A PCI card€ 1‘000.- Catscience Matlab camera interface€ 320.- Appr. Total costs€ 48‘320.- Time schedule 1st concurrent MROI scans December 2004 Bruno Weber, Nov 2004