1. Amino Acids Stryer Short Course Chapter 3

2. Amino Acid Structure Alpha carbon Sidechain Proteins peptides

3. Stereochemisty L-amino acids – Glycine – R/S vs D/L – L-isoleucine racemization

4. Ionization of Amino Acids Polyprotic acids Alanine – pKa 1 = 2.4 – pKa 2 = 9.9 Zwitterion Isoelectric point More acidic than typical carboxylic acid

5. Polyprotic Acids

6. Common Amino Acids

7. Hydrophobic Or polar

8. Hydrophobic

10. Polar

12. Positively Charged Or polar

13. Negatively Charged

14. Acid/base chemistry Charged amino acids Other amino acids are ionizable

15. Which amino acid(s)... Is achiral? Has a secondary amino group? Has a chiral sidechain? Form these derivatives:

16. Titration Curve

17. Which amino acid?

18. Ionization States Of Amino Acids A B C D E F G

19. Essential Amino Acids Dietary Term Can change in stage of life Depends on definition of biosynthetic building blocks