1. 1 Cardiovascular Disease in Asia

2. WHO CVD Atlas. 2002. WHO Stroke Atlas. 2002. The Burden of CVD in Asia: Stroke Deaths by Country, 2002 2

3. Projected Stroke and CHD increase to 2030 in China Moran et al. Circ Cardiovasc Qual Outcomes. 2010;3;243-252. 3

4. South-East Asia: deaths in 2000 attributable to selected leading risk factors Blood pressure Underweight Tobacco Cholesterol Fruit and vegetable intake Unsafe water, sanitation and hygiene Indoor smoke from solid fuels Physical inactivity Unsafe sex Iron deficiency Zinc deficiency High body mass index Alcohol Vitamin A deficiency Unsafe health care infections 050010001500 Number of deaths (000s) World Health Report 2002

5. Age-Standardized Stroke and CHD Death Rates by Country, 2002 Ueshima H et al. Circulation. 2008;118:2702-2709. 5

6. Classic Cardiovascular Risk Factors are Consistent and Common within the Symptomatic REACH Registry Baseline Population *1 1. Bhatt DL et al, on behalf of the REACH Registry Investigators. JAMA 2006; 295(2): 180-189. Risk Factor Prevalence, Symptomatic Population (% of symptomatic population) 1 *Symptomatic refers to patients with documented Coronary artery, Cerebro and/or Peripheral Arterial Disease; data shown may differ slightly from published abstracts owing to a subsequent database lock.