1. Membrane Transport

2.  What are some substances commonly transported across membranes?

3. Membrane Transport  What are the three mechanisms used to move solute molecules across the membrane?

4. Simple Diffusion  What is involved in this transport process?  What can cross the plasma membrane via simple diffusion?

5. Simple Diffusion  How does osmosis differ from simple diffusion?

6. Simple Diffusion  What are the major factors that influence diffusion across a membrane?

7. Simple Diffusion  What specifically determines the rate of simple diffusion? v inward = PΔS P = permeability coefficient ΔS = concentration gradient

8. Simple Diffusion  What is the partition coefficient and how does it affect diffusion?

9. Facilitated Diffusion  How is facilitated diffusion different from simple diffusion?

10. Facilitated Diffusion  What do we know about transporters?  What is the difference between a transporter or carrier protein and a channel protein?

11. Facilitated Diffusion

12.  In what ways do transporters resemble enzymes?  What kinds of molecules are transported via facilitated diffusion?

13. Facilitated Diffusion  What do we specifically know about the transport of glucose in red blood cells?

14. Facilitated Diffusion  What is the difference between ion channels, porins and aquaporins?

15. Active Transport  How is active transport similar to and different from facilitated diffusion?

16. Active Transport  What is the difference between direct and indirect active transport?

17. Active Transport  How can we calculate the energy needed to transport uncharged molecules across a membrane? ΔG = RT ln [S] inside /[S] outside free energy need to transport molecules from outside to inside of membrane

18. Active Transport  If the solute being transported has a charge how does that affect the energy requirement? ΔG = RT ln [S] inside /[S] outside + zFV m z = charge on ion F = 23,062 cal/mol-V (Faraday constant) Vm = membrane potential – in volts Sum of concentration & charge gradients = electrochemical gradient

19. Active Transport  What are the four types of transport ATPases?

20. Active Transport  What do we currently know about the sodium-potassium pump?

21. Active Transport

22.  Why is this sodium-potassium pump so important for animal cells?

23. Active Transport  Why is the Na + /glucose symporter an example of indirect active transport?

24. Active Transport

25.  What does the bacteriodopsin pump do and where is it found?

26. Active Transport