2. © Mark E. Damon - All Rights Reserved

3. Another Presentation © 2001 - All rights Reserved markedamon@hotmail.com

4. © Mark E. Damon - All Rights Reserved Directions: To play, select different money amounts from each category. If you (Player #1) pick it, you go first and if you get it right, you win the money. If you miss it, you lose the money! The next person (Player #2) gets to try, but if he/she misses it, no points lost! Same thing with Player #3 if he/she misses it. Then it’s back to Player #2’s turn to pick a question, and so on. As you play the game, click on the $DOLLAR AMOUNT, not the surrounding box. Keep track of which questions have already been picked on your worksheet.

5. © Mark E. Damon - All Rights Reserved Directions: After a question is picked, click again anywhere on the screen to see the correct answer. On your notes sheet, now record what you have learned to help you study. Click on the “Scores” box in the bottom right hand corner to return to the questions. Enter the score into the black box on each player’s podium for the question you just finished. Continue until all clues are given. Then play “Final Jeopardy”. To play “Final Jeopardy”, secretly bet a portion of your winnings so far on the question. He/she can choose any amount to either add or subtract from their winnings based on the category they know the question will be from. Then the final answer is revealed, and all 3 players write on their own papers their answer. When the correct question is revealed, all three players should share their answers and their wagers to see who has won!

6. © Mark E. Damon - All Rights Reserved Round 1 Final Jeopardy

7. © Mark E. Damon - All Rights Reserved Clinical Trials Elements of Good Experimental Design Problem Solving Methods Analyzing Data Vocab Potpourri $100 $200 $300 $400 $500 Final Jeopardy Scores

8. © Mark E. Damon - All Rights Reserved $100 What is the purpose of a Clinical Trial? Hint: To make sure the medicine is ____ & ____.

9. © Mark E. Damon - All Rights Reserved $100 To make sure the medicine is safe and effective Scores

10. © Mark E. Damon - All Rights Reserved $200 What is the difference between a control and treatment group?

11. © Mark E. Damon - All Rights Reserved $200 Scores The control group thinks that they are getting the medicine but get an inactive substance where as the treatment group actually get the medicine.

12. © Mark E. Damon - All Rights Reserved $300 A Placebo is a type of…

13. © Mark E. Damon - All Rights Reserved $300 Scores Control

14. © Mark E. Damon - All Rights Reserved $400 In a clinical trial, why is a placebo group included?

15. © Mark E. Damon - All Rights Reserved $400 It is used as a comparison to assure that the medicine is actually working and that the patient is not getting better because of the placebo effect. Scores

16. © Mark E. Damon - All Rights Reserved $500 SameBetter Control Group 255 Treatment Group 1020 How many people experienced the placebo effect from the data below?

17. © Mark E. Damon - All Rights Reserved $500 Scores 5

18. © Mark E. Damon - All Rights Reserved $100 Which is better, a large or small sample size?

19. © Mark E. Damon - All Rights Reserved $100 large Scores

20. © Mark E. Damon - All Rights Reserved $200 What does it mean for a experiment to be reproducible?

21. © Mark E. Damon - All Rights Reserved $200 So that anyone else can take your procedures and understand exactly what you did and be able to conduct your experiment and get similar results. Scores

22. © Mark E. Damon - All Rights Reserved $300 What are the two kinds of data?

23. © Mark E. Damon - All Rights Reserved $300 Qualitative and Quantitative Data Scores

24. © Mark E. Damon - All Rights Reserved

25. $400 What are the 2 kinds of variables found in an experiment?

26. © Mark E. Damon - All Rights Reserved $400 Tested Variable and Control Variables Scores

27. © Mark E. Damon - All Rights Reserved $500 Rosey wants to test whether feeding her twin sisters sugar will affect their growth. She will feed one sister sugar and not the other one. What would be considered her control?

28. © Mark E. Damon - All Rights Reserved $500 Scores The sister who does not receive sugar.

29. © Mark E. Damon - All Rights Reserved $100 What is a hypothesis?

30. © Mark E. Damon - All Rights Reserved $100 Scores A prediction of the answer to the problem in an experiment, it is based on background knowledge and observations.

31. © Mark E. Damon - All Rights Reserved $200 Is the traditional scientific method used by all scientists? Why or why not?

32. © Mark E. Damon - All Rights Reserved $200 Answers may vary. All scientist conduct experiments in similar ways and usually have some component of the TSM, but…all problems are different and need different methods to solve them. Scores

33. © Mark E. Damon - All Rights Reserved $300 Name 2 essentials of good procedure.

34. © Mark E. Damon - All Rights Reserved $300 1.Numbered Steps 2. Detailed 3.Clear and easy to follow. 1.Numbered Steps 2. Detailed 3.Clear and easy to follow. Scores

35. © Mark E. Damon - All Rights Reserved $400 Name 1 way Dr. Goldberger’s problem solving method was different from the traditional scientific method.

36. © Mark E. Damon - All Rights Reserved $400 Scores Answers will vary….he made observations before making his hypothesis and also published his conclusions.

37. © Mark E. Damon - All Rights Reserved $500 Name 1 problem solving step that some scientist's don’t use and 1 problem solving step all scientists use.

38. © Mark E. Damon - All Rights Reserved $500 Answers will vary…one step some scientists don’t use is not all scientists form a hypothesis before they test. Two steps all scientists use is stating the problem and collecting data. Scores

39. © Mark E. Damon - All Rights Reserved $100 What does it mean to analyze the data?

40. © Mark E. Damon - All Rights Reserved $100 Analyzing data means you examine the data and observations you have collected, and attempt to make connections between your data and the problem you are solving. Scientists often do this by looking for trends and patterns in the data. Scores

41. © Mark E. Damon - All Rights Reserved $200 In a clinical trial, 15 out of 100 patients in the control group got side effects. In the treatment group, 14 out of 100 people also got side effects. Explain what conclusions you can make about the safety of the medicine from this data.

42. © Mark E. Damon - All Rights Reserved $200 Scores The medicine isn’t much less safe than the placebo, since it was almost the same # of people who got side effects in both groups. The side effects are probably not a result of the active ingredient.

43. © Mark E. Damon - All Rights Reserved $300 If Study A tests their medicine on 100 people and Study B tests theirs on 1000, which study would you fund based only on this information? Why?

44. © Mark E. Damon - All Rights Reserved $300 Study B because it has a larger sample size and a greater chance of seeing all of the possible scenarios in the patients. Scores

45. © Mark E. Damon - All Rights Reserved $400 What two options does a scientist have after analyzing his/her data?

46. © Mark E. Damon - All Rights Reserved $400 Make a conclusion or do another experiment. Scores

47. © Mark E. Damon - All Rights Reserved $500 Which is easier to analyze, qualitative or quantitative data? Why?

48. © Mark E. Damon - All Rights Reserved $500 Usually quantitative, because the data is countable or measurable and can easily be graphed to see trends. Scores

49. © Mark E. Damon - All Rights Reserved $100 The available facts, data, and or observations which support a theory or conclusion.

50. © Mark E. Damon - All Rights Reserved $100 Scores Evidence

51. © Mark E. Damon - All Rights Reserved $200 The act of conducting a controlled test or investigation.

52. © Mark E. Damon - All Rights Reserved $200 Experiment. Scores

53. © Mark E. Damon - All Rights Reserved $300 The one factor that a scientist changes during an experiment.

54. © Mark E. Damon - All Rights Reserved $300 Tested variable Scores

55. © Mark E. Damon - All Rights Reserved $400 A set of values.

56. © Mark E. Damon - All Rights Reserved $400 Range. Scores

57. © Mark E. Damon - All Rights Reserved $500 What does NIH stand for?

58. © Mark E. Damon - All Rights Reserved $500 National Institute of Health Scores

59. © Mark E. Damon - All Rights Reserved $100 What is a variable?

60. © Mark E. Damon - All Rights Reserved $100 It is a factor that is changed or controlled in order to isolate and identify what is causing the observed effect. Scores

61. © Mark E. Damon - All Rights Reserved $200 What is a controlled variable?

62. © Mark E. Damon - All Rights Reserved $200 A variable that you keep the same so that you can isolate the tested variable. Scores

63. © Mark E. Damon - All Rights Reserved $300 Describe the difference between qualitative and quantitative data.

64. © Mark E. Damon - All Rights Reserved $300 Qualitative Data- is data that difficult to count or measure because it is usually a description of something. Quantitative Data can easily be counted or measured because it is collected as numbers. Scores

65. © Mark E. Damon - All Rights Reserved $400 What is a trade-off? Give an example of a trade off.

66. © Mark E. Damon - All Rights Reserved $400 Scores Trade-off: An exchange of one thing in return for another, giving up one benefit or advantage for another regarded as more desirable; an exchange that occurs as a compromise; "I faced a tradeoff between hanging out with my friends or studying for the test so I could get an A”

67. © Mark E. Damon - All Rights Reserved $500 In our “Data Toss Part 1” Activity, name the variable we were testing and two variables we controlled.

68. © Mark E. Damon - All Rights Reserved $500 Tested variable: 1 or 2 handed catch Controlled Variables: speed, distance, type of ball, type of throw, etc. Scores

69. © Mark E. Damon - All Rights Reserved Scores Final Jeopary Question Experimental Design

70. © Mark E. Damon - All Rights Reserved Name 6 of the 10 elements of good experimental design.

71. © Mark E. Damon - All Rights Reserved Scores -builds on previous research -describes all steps in procedure clearly and completely -describes all data to be collected -keeps all variables, except the one being tested, the same -includes a control (or placebo) for comparison -uses an appropriate group of subjects -may include a large sample size -may include multiple trials -can be reproduced by other investigators to give -similar results -respects human and animal subjects -builds on previous research -describes all steps in procedure clearly and completely -describes all data to be collected -keeps all variables, except the one being tested, the same -includes a control (or placebo) for comparison -uses an appropriate group of subjects -may include a large sample size -may include multiple trials -can be reproduced by other investigators to give -similar results -respects human and animal subjects