1. Implementing Online Training at a Large Academic Institution Strategies and Solutions for Integrating Web-based Training in Animal Care and Use Programs

2. A Tale of Two Institutions: Instituting the ALL as a training program

3. A Tale of Two Institutions: Administering the ALL as a training program

4. The Institution

6. #1 Cancer Center in the US #1 Cancer Center in the US highest $ amount of NCI supported research in the US highest $ amount of NCI supported research in the US 1350 faculty 1350 faculty 736 valid animal protocols 736 valid animal protocols 319 principal investigators 319 principal investigators more than 3000 animal users more than 3000 animal users >50% of animal users are NOT native English speakers >50% of animal users are NOT native English speakers

7. The Process of Instituting a New Program Background: IACUCs were first required in 1985, and MDA has been AAALAC accredited since 1979 - so we may have had some level of training requirement since that time. IACUCs were first required in 1985, and MDA has been AAALAC accredited since 1979 - so we may have had some level of training requirement since that time. Training programs had not been updated for at least 15 years. Training programs had not been updated for at least 15 years.

8. Training prior to 9/07

9. The Process of Instituting a New Program Casual conversation Casual conversation Meeting with the head veterinarian and IACUC coordinator Meeting with the head veterinarian and IACUC coordinator Presentation to the IACUC Presentation to the IACUC Study committee Study committee Proposal to the IACUC Proposal to the IACUC Approval of funding by the AVP for Research Approval of funding by the AVP for Research Proposal to the chairs of the science faculty Proposal to the chairs of the science faculty Mandate from the Provost for all investigators Mandate from the Provost for all investigators

10. The Process of Instituting a New Program Some of the reasons for updating the training program to the ALL: 1) convenience of online training, 2) quality and relevance of the AALAS materials, 3) ability to standardize training among institutions and transfer/accept training certification from other institutions.

11. Implementing and administering the ALL as a training program Founded in 1870 as a land grant university The LARGEST university in the US The major institution is in Columbus, OH There are 5 branch campuses spread throughout Ohio There are 6 additional off-campus research facilities, 2 that perform animal research 5,377 faculty 1050 active protocols 1331 personnel trained in animal care.

12. Implementing and administering the ALL as a training program A job of “Titanic” proportions Goal: Replace the current OSU on-line version with one that has more current information, is comprehensive and meets current regulations

13. Implementing and administering the ALL as a training program Previous Training Program: 1)Online training through ResearchTraining.org (required): For academic trainees, investigators, and animal care staff About 1500 people trained each year 2)OSU classroom course (optional): For academic trainees, investigators and animal care staff Students are grouped by ability/topic Used in addition to online training to cover special topics and answer questions. About 300-400 people trained/year

14. Implementing and administering the ALL as a training program OSU On-line Course 1. Introduction 2. Working with the IACUC 3. Federal mandates 4. The veterinary consultation 5. Getting started 6. Alternatives 7. Avoiding unnecessary duplication 8. Early removal criteria 9. Personnel training and experience 10. Occupational health and safety 11. Using hazardous and toxic agents in animals 12. Euthanasia 13. Making changes after you receive approval 14. Reporting misuse, mistreatment, or non-compliance 15. Final comments ________________________________

15. Implementing and administering the ALL as a training program OSU Classroom Course 1. State and federal regulations and agencies 2. The protocol document and the IACUC 3. Available guidelines for various species 4. Record keeping 5. Biohazardous agents and EH&S training 6. Analgesic and anaesthetic techniques 7. Euthanasia techniques 8. Recognition of pain and distress and measures to obviate it 9. Rationale for using animals 10. Animal welfare versus animal rights philosophies 11. Alternatives to replace live animals 12. Usage of minimal sample size 13. Zoonoses- particularly allergy and non-human primate 14. Environmental Health and Safety requirements 15. Employee health services registration & surveillance 16. Hands-on animal workshops- availability

16. Implementing and administering the ALL as a training program OSU On-line Course (continued) 16. Surgery 17. Antibody production 18. Collecting blood samples 19. Housing social animals 20. Housing rodents on wire floors 21. Dog exercise 22. Primate psychological enrichment 23. Prolonged restraint 24. Using explosive agents in the animal facility

17. Implementing and administering the ALL as a training program Questions/Comments: 1. What is needed is an on-line training module that has current information, is comprehensive, but is not too burdensome. 2. How similar do the classroom version and the on-line version need to be? Can the ALL substitute for present online training? 3. Could the classroom version be a sufficiently comprehensive PowerPoint presentation that could be posted on-line? Advantage: identical format for both versions.

18. Implementing and administering the ALL as a training program AALAS On-line Modules Introduction to research animal Working with the IACUC Ethical decision-making in animal research courses Biosafety in microbiologic and biomedical laboratories Workplace training Examination _____________________________________________

19. Implementing and administering the ALL as a training program AALAS On-line Modules (continued) US federal mandates courses Anesthesia and analgesia Methodologies Videos/CDs on biomethodology Nonhuman primates courses Mouse biomethodology courses Basic metrics for the laboratory animal facility Selection of cage cleaner products - chemistry driven Writing multiple choice questions Laboratory animal medicine Ergonomics courses Communication skills Aseptic technique for rodent survival surgery Time and project management Facilities, supplies, and materials Dog biomethodology courses ALAT courses LAT courses LATG courses Taking an AALAS technician certification

20. Prerequisites for Establishing Integrated Web Based Training Incentive Compliance Institutional Support Funding IT Support Synergy Between Units IACUC Motivation Interact with AALAS

21. Thanks To: Peggy Tinkey Lydia Jackson Kate Naff Leisa McCord Larry Capitini Kim Swider (Longnecker) Earle Holland