1. Lior Z. Braunstein MD 1, Andrzej Niemierko PhD 2, Mina N. Shenouda MD 2, Linh Truong 3, Betro T. Sadek MD 2, Rita Abi Raad MD 2, Julia S. Wong MD 3, Rinaa S. Punglia MD MPH 3, Alphonse G. Taghian MD PhD 2, Jennifer R. Bellon MD 3 1 Harvard Radiation Oncology Program; Depts of Radiation Oncology, 2 Massachusetts General Hospital and 3 Brigham and Women’s Hospital and Dana Farber Cancer Institute Harvard Radiation Oncology Program Outcome following local-regional recurrence in women with early stage breast cancer: Impact of biologic subtype ASTRO Annual Meeting, September 2014 Session (DPD 03) Breast.

2. Baseline patient cohort. Among LRR, in-breast recurrence was the most common site. Surgery was universally offered for recurrence.

3. Significant predictors of LRR. Triple negative subtype was the most adverse predictor of DFS following LRR. Size of initial tumor and use of salvage surgery were also associated with DFS.

4. DFS following LRR by subtype.