2. Respiration Metabolism

3. Respiration

5. Semilunar valves Left ventricle Left atrium Right atrium Right ventricle ostia Atrioventricular valves

7. -Regulation of SA and AV nodes: Nervous: Sympathetic vs. Parasympathetic (vagus) Hormones: Epi, ACh, Temperature, Exercise, pH these also effect blood vessels (constrict or relax PR) The Heart: Control -Cardiac cells: myogenic (self-excitable) in syncytium Controlled by sinoatrial (SA) node, the pacemaker. 1st: Atrial electrical wave -> two atria contract 2nd: Wave at atrioventricular (AV) node, delayed 0.1s 3rd: Common bundle & Purkinje fibers to Ventricles

8. Sinoatrial node Atrioventricular node Conducting fibers Left ventricle Left atrium Right atrium Right ventricle

9. 00.1 Electrical activity in atria SA node activates atria AV node delay Electrical activity in ventricles Ventricles recover 0.2 Time (seconds) 0.30.40.5

10. Fig. 42-9-1 Pacemaker generates wave of signals to contract. 1 SA node (pacemaker) ECG

11. Fig. 42-9-2 Signals are delayed at AV node. 2 AV node

12. Fig. 42-9-3 Signals pass to heart apex. 3 Bundle branches Heart apex

13. Fig. 42-9-4 Signals spread throughout ventricles. 4 Purkinje fibers Be the HEART and Depolarize

14. The Heart: Function -Function pump blood; create pressure gradient. Contraction and relaxation =cardiac cycle During systole, muscle contracts and pumps During diastole, muscle relaxes and chambers fill Sounds “Lub” AV, “Dub” SL, “ssssshh” murmur.

17. Blood returning to the mammalian heart in a pulmonary vein drains first into the a)vena cava. b)left atrium. c)right atrium. d)left ventricle. e)right ventricle.

18. Heart valves function to _____. a) keep blood moving forward through the heart b) mix blood thoroughly as it passes through the heart c) control the amount of blood pumped by the heart d) slow blood down as it passes through the heart e) propel blood as it passes through the heart

19. The Basics of Circulation

22. Fig. 42-14 Direction of blood flow in vein (toward heart) Valve (open) Skeletal muscle Valve (closed)

23. Compared with the interstitial fluid that bathes active muscle cells, blood reaching these cells in arteries has a a)higher PO2. b)higher PCO2. c)greater bicarbonate concentration. d)lower pH. e)lower osmotic pressure.

24. What is unique about blood in pulmonary arteries compared with blood in other arteries? a) Blood in pulmonary arteries is always blue; it is red in all other arteries. b) It is moving away from the heart. c) It is moving toward the heart. d) It is the same as blood in other arteries. e) It is loaded with carbon dioxide.