1. Chapter 14 DNA: The Molecule of Heredity

2. The Beginning of the Era 1800s – Scientists have discovered that traits are passed down through generations The discrete units are called genes Genes are associated with a thread- like material in nuclei called chromosomes Chromosomes are made of nucleic acids and proteins

3. Which chemical is responsible for the passage of traits?

4. Fredrick Griffiths 1920s Utilizing Streptococcus pneumoniae Strain differences “Transforming Factor”

5. Avery, MacLeod, and McCarty 1940s Reworked Griffith’s experiment Utilized technology not available to Griffith Purified classes of macromolecules

6. DNA is the carrier of heredity!

7. How does DNA accomplish transfer of information?

8. DNA Bases

9. Key Evidence – X-Ray Data

10. The Players in Discovering the Structure Erwin Chargaff Linus Pauling Maurice Wilkins and Rosalind Franklin James Watson and Francis Crick

11. The Double Helix

12. Replication

13. Chapter 10 Transcription and Translation

14. RNA

15. Genetic Code

16. Translation

17. Translation (cont.)

22. Flow of Information

23. Mutation