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Dinah Callender, RN The Pennsylvania State University
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Describe the lab-on-a- chip Describe the hardware used in the trend Review Software Define Axioms Review Criteria Describe Advantages and Disadvantages
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Ethics and Legal issues Describe informatics nurse using the chip Summarize the lab on a chip
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Instrument that integrates one or several laboratory functions Only millimeters to centimeters in size
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Few drops of blood needed to function Invented to perform blood analyses
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Laptop or PDA Semiconductor Chip Special Camera Handheld device controller
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Semiconductor chip Made of Silicon Glass Plastic Paper
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Some of the software used in the chips created by Agilent Technologies are: Compliance solution RNA Solution Mass spectrometry software 2100 Expert Software
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2100 Expert Software for the Agilent 2100 Bioanalyzer -offers powerful data evaluation tools for all available assays - automatic and manual integration - smear analysis and many assay-specific tool.
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Axiom 1- meets goal of user Axiom 2 the software allows for evaluation and correction Axiom 3- needs to be determined.
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Designed to collect patient data Improves care by making data accessible Patient-focused
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This is a clinical information system Used by physicians, nurses, and pharmacist Enables documentation The Configuration utilized is point of care Data standard used is Healthlevel 7 (HL7) Disease and Procedure Classification System (Northrop Grumman, 2010)
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Nursing practice standards classification scheme
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A decrease or no human mistakes Can find bacteria, viruses, and cancers Can extract DNA from cells Cost effective Small amount of blood needed
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Chip is new on the scene Not yet mature People may be reluctant
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Lab on a chip utilizes wireless communication Utilizes expert systems to develop diagnoses Raises concern about privacy and legal responsibility Personal health information widely accessible
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Beginning nurse would be able to : Retrieve information obtains results from patient monitoring system Understands lab on a chip’s limitations Experienced nurse Troubleshoots problems Places monitoring systems
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Informatics nurse specialist Will provide training programs Foresees impacts on staff and patients Makes lab on a chip user friendly Informatics Innovator Develops sample trials Does advanced analysis
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Provides the education on how to use the chip Show ways to troubleshoot any problems Research to create new knowledge Utilizes tools to maintain data integrity
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A mini-lab on a polymer chip Uses small volumes of blood/ fluid Fluids moved by pressure through channels Used for mixing, dilution, staining Detection on single integrated systems
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Agilent Technologies.(July, 2009). 2100 Expert Software. Retrieved on March17,2010,from www.chem.agilent.com/enus/products/instruments/ labonachip/2100bioanalyzer/smallrnaassay/ CBC News (2009, Oct.7). Breast cancer ‘lab on a chip’ developed. Retrieved on March17,2010, fromhttp://www.cbc.ca/health/story/2009/10/07/bre ast-cancer-chip.http://www.cbc.ca/health/story/2009/10/07/bre ast-cancer-chip Northrop Grumman (2010). Clinical Information System. Retrieved on April 17, 2010, from http://www.is.northropgrumman.com/by_soluti on/health_it/markets/health_cis/index.html
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Insight:Lab on a chip (July 26, 2006). Nature. Retrieved on March 17, 2010, from http://www.nature.com/nature/journal/v442/n7101/full/4 42367a.html http://www.nature.com/nature/journal/v442/n7101/full/4 42367a.html Lab-on-a-chip. Retrieved March 17, 2010, from http://en.wikipedia.org/wiki/Lab-on-a-chip Societal and Ethical Interactions with Nanotechnology (SEIN)-An Introduction (April, 2005). SOCIETY ETHICS_BAIRD VOGTTOSEND[1].Retrieved April 18,2010,from http://arxiv.org/ftp/physics/papers/0504/0504007.pdf
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