1. Narcolepsy By: Emeline Vinkenes and Sunniva Kruse Johannesen

2. What is Narcolepsy? A chronic sleeping disorder Hard to stay awake for longer periods of time Sudden attacks of sleep Can fall a sleep under any circumstances

3. Symptoms Excessive daytime sleeping Sudden loss of muscle tone Sleeping paralysis Hallucinations Low levels of Hypocretin/Orexin

4. Causes Not exact known Genetics Infections Sleeping pattern – NREM + REM Hypocretin level H1N1 vaccination

5. Statistics Most common age of diagnostics is 20-40 years. Affect 0.05% of the population world wide

6. Treatments and drugs No cure Stimulates: - Modafilin - Methylphenidate Selective serotonin reuptake inhibitors: - Fluoxetine - Venlafaxine Tricyclic antidepressants: - Protriptyline - Imipramine - Clomipramine Sodium oxybate (Xyrem)

7. Daily life Recommendations: - Naps during the day - Exercise - No nicotine and alcohol - Consistent sleeping schedule Complications: - Public misunderstanding - Feelings and relationships - Physical harm - Obesity

8. Sources http://www.mayoclinic.com/health/narcoleps y/DS00345 http://www.mayoclinic.com/health/narcoleps y/DS00345 http://www.cdc.gov/vaccinesafety/Concerns/ h1n1_narcolepsy_pandemrix.html http://www.cdc.gov/vaccinesafety/Concerns/ h1n1_narcolepsy_pandemrix.html http://www.narcolepsy.org.uk/about- narcolepsy/who-does-it-affect http://www.narcolepsy.org.uk/about- narcolepsy/who-does-it-affect http://www.sleepeducation.com/sleep- disorders/narcolepsy/treatment http://www.sleepeducation.com/sleep- disorders/narcolepsy/treatment