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Immune 2 Renal 1 Renal 2 Misc. Immune 1 10 20 30 40 50 40 30 20 10 50 40 30 20 10 50 40 30 20 10 50 40 30 20 10
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QUESTION: What is the functional unit of the kidney? ANSWER: Nephron
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QUESTION: Name two types of nephrons. ANSWER: Cortical Juxtamedullary
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QUESTION: What are the three protective layers surrounding the kidney? ANSWER: Renal fascia Perirenal fat capsule Fibrous capsule
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QUESTION: Name the parts of the renal tubule. ANSWER: PCT Descending LOH Ascending LOH DCT Collecting ducts
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QUESTION: Trace the blood flow through the nephron. ANSWER: Afferent arteriole Glomerulus Efferent arteriole Peritubular capillaries Vasa recta
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QUESTION: What do the cells in the PCT look like? ANSWER: Microvilli Mitochondria
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QUESTION: What is the function of the DCT? ANSWER: Secretion
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QUESTION: What is the function of intercalated cells and principal cells? ANSWER: Intercalated – Maintain acid-base balance Principal – Water and salt regulation
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QUESTION: Describe how the myogenic mechanism works. ANSWER: When blood pressure goes up, afferent arterioles constrict to slow down GFR When blood pressure goes down, afferent arterioles dilate to speed up GFR
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QUESTION: What are the three stages of urine formation? ANSWER: Glomerular filtration Tubular reabsorption Tubular secretion
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QUESTION: What is the defining characteristic of NK cells? ANSWER: Not phagocytic
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QUESTION: Name the three layers of the filtration membrane. ANSWER: Capillary endothelium Basement membrane Podocyte
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QUESTION: Name three hormones in the renal system and what they do. ANSWER: Parathyroid hormone – regulates calcium levels ADH – water regulation Aldosterone – sodium regulation
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QUESTION: What are the four stages of phagocyte mobilization? ANSWER: Leukocytosis Margination Diapedesis Chemotaxis
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QUESTION: Describe how the tubuloglomerular feedback mechanism works. ANSWER: When salt levels are high, macula densa cells of JGA release vasoconstricting chemical Afferent arteriole constricts, GFR decreases
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QUESTION: Name two barriers in the first line of defense. ANSWER: Skin Mucous membranes
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QUESTION: Name two cell types that are a part of the second line of defense. ANSWER: Macrophages Neutrophils Natural killer cells Phagocytes
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QUESTION: What are two signs of the inflammatory response? ANSWER: Swelling Redness Heat Pain
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QUESTION: Name two characteristics of the adaptive immune system. ANSWER: Antigen specific Systemic Has memory
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QUESTION: What does SCID and AIDS stand for? ANSWER: Severe combined immunodeficiency Acquired immunodeficiency syndrome
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QUESTION: Where do T-cells and B-cells mature? ANSWER: Thymus Bone marrow
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QUESTION: How can an organism acquire immunity actively? ANSWER: Having an infection Vaccinations
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QUESTION: What is one type of passive immunity? ANSWER: Donor antibodies Mother’s antibodies
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QUESTION: What type of protein recognizes normal cells as “self?” ANSWER: Class I major histocompatibility complex proteins (MHC)
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QUESTION: What is one autoimmune disease? ANSWER: Rheumatoid arthritis Multiple sclerosis
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