1. Hole’s Human Anatomy and Physiology Tenth Edition Shier  Butler  Lewis Chapter 5 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 5-1 PowerPoint Lecture Outlines to accompany

2. Chapter 5 Tissues Four major tissue types 1. Epithelial 2. Connective 3. Muscle 4. Nervous 5-2

3. Epithelial Tissues General characteristics - cover organs and the body line body cavities line hollow organs have a free surface have a basement membrane avascular cells readily divide cells tightly packed cells often have desmosomes function in protection, secretion, absorption, and excretion classified according to cell shape and number of cell layers 5-3

4. Epithelial Tissues Simple squamous – single layer of flat cells substances pass easily through line air sacs line blood vessels line lymphatic vessels Simple cuboidal – single layer of cube-shaped cells line kidney tubules cover ovaries line ducts of some glands 5-4

5. Epithelial Tissues Simple columnar – single layer of elongated cells sometimes possess cilia sometimes possess microvilli often have goblet cells line uterus, stomach, intestines Pseudostratified columnar – single layer of elongated cells appear striated often have cilia often have goblet cells line respiratory passageways 5-5

6. Epithelial Tissues Stratified squamous – many cell layers top cells are flat can accumulate keratin outer layer of skin line oral cavity, throat, vagina, and anal canal Stratified cuboidal – 2-3 layers cube-shaped cells line ducts of mammary glands, sweat glands, salivary glands, and the pancreas 5-6

7. Epithelial Tissues Stratified columnar – top layer of elongated cells cube-shaped cells in deeper layers line vas deferens, male urethra, and part of pharynx Transitional – many cell layers cube-shaped and elongated cells line urinary bladder, ureters, and part of urethra 5-7

8. Glandular Epithelium Composed of cells that are specialized to produce and secrete substances Endocrine glands are ductless Exocrine glands have ducts Unicellular exocrine gland composed of one cell goblet cell Multicellular exocrine gland composed of many cells sweat glands, salivary glands, etc. 5-8

9. Structural Types of Exocrine Glands 5-9

10. Types of Glandular Secretions Merocrine glands fluid product salivary glands pancreas sweat glands Apocrine glands cellular product portions of cells mammary glands ceruminous glands Holocrine glands secretory products whole cells sebaceous glands 5-10

11. Connective Tissues General characteristics - most abundant tissue type many functions bind structures provide support and protection serve as frameworks fill spaces store fat produce blood cells protect against infections help repair tissue damage have a matrix have varying degrees of vascularity have cells that usually divide 5-11

12. Connective Tissue Major Cell Types Fibroblasts fixed cell most common cell large, star-shaped produce fibers Macrophages wandering cell phagocytic important in defense Mast cells fixed cell release heparin release histamine 5-12

13. Connective Tissue Fibers Collagenous fibers thick composed of collagen great tensile strength abundant in dense CT hold structures together tendons, ligaments Elastic fibers bundles of microfibrils embedded in elastin fibers branch elastic vocal cords, air passages Reticular fibers very thin collagenous fibers highly branched form supportive networks 5-13

14. Connective Tissues Connective tissue proper loose connective tissue adipose tissue reticular connective tissue dense connective tissue elastic connective tissue Specialized connective tissue cartilage bone blood 5-14

15. Connective Tissues Loose connective tissue mainly fibroblasts fluid to gel-like matrix collagenous fibers elastic fibers bind skin to structures beneath most epithelia between muscles Adipose tissue adipocytes cushions insulates store fats beneath skin behind eyes around kidneys and heart 5-15

16. Connective Tissues Reticular connective tissue composed of reticular fibers supports walls of liver, spleen, lymphatic organs Dense connective tissue packed collagenous fibers elastic fibers few fibroblasts bind body parts together tendons, ligaments, dermis poor blood supply 5-16

17. Connective Tissues Elastic connective tissue abundant in elastic fibers some collagenous fibers fibroblasts attachments between vertebrae walls of large arteries, airways, heart Bone solid matrix supports protects forms blood cells attachment for muscles skeleton osteocytes in lacunae 5-17

18. Connective Tissues Cartilage rigid matrix chondrocytes in lacunae poor blood supply three types hyaline elastic fibrocartilage Hyaline cartilage most abundant ends of bones nose, respiratory passages embryonic skeleton Elastic cartilage flexible external ear, larynx Fibrocartilage very tough shock absorber intervertebral discs pads of knee and pelvic girdle 5-18

19. Connective Tissues Three types of cartilage 5-19

20. Connective Tissues Blood fluid matrix called plasma red blood cells white blood cells platelets transports defends clotting throughout body in blood vessels heart 5-20

21. Muscle Tissues General characteristics muscle cells called muscle fibers contractile three types skeletal smooth cardiac Skeletal muscle attached to bones striated voluntary Smooth muscle walls of organs skin walls of blood vessels involuntary not striated Cardiac muscle heart wall involuntary striated intercalated discs 5-21

22. Muscle Tissues 5-22

23. Nervous Tissues found in brain, spinal cord, and peripheral nerves basic cells are neurons neuroglial cells are supporting cells sensory reception conduction of nerve impulses 5-23

24. Types of Epithelial Membranes Serous line body cavities that lack openings to outside reduce friction inner lining of thorax and abdomen cover organs of thorax and abdomen secrete serous fluid Mucous line tubes and organs that open to outside world lining of mouth, nose, throat, etc. secrete mucus Cutaneous covers body skin 5-24

25. Clinical Application Collagen Disorders Chondrodysplasia collagen chains too wide stunted growth deformed joints Dystrophic epidermolysis bullosa breakdown of collagen that attaches skin layers stretchy skin lax joints Hereditary osteoarthritis change in amino acid in collagen painful joints 5-25

26. Which of the following is not a major tissue type: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Bone 2.Muscle 3.Nerve 4.Connective 5.Eptithelial

27. This tissue covers body surfaces and lines organs: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Bone 2.Nervous 3.Epithelial 4.Muscle 5.Connective

28. Which of the following is a function of connective tissue: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Bind and support 2.Store fat 3.Carry oxygen 4.Fill spaces 5.All of these

29. Two minerals that make bone hard are: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Iron and magnesium 2.Calcium and potassium 3.Calcium and phosphorous 4.Sodium and chloride 5.Sodium and fluoride

30. Another word for the central canal of bone tissue: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Haversian canal 2.Lacuna canal 3.Canaliculi 4.Lamellae 5.Osteocyte

31. Muscle that is voluntary is: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Cardiac 2.Smooth 3.Skeletal 4.Both 1 and 2 5.Both 2 and 3

32. Smooth muscle is found in the: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Stomach 2.Intestines 3.Uterus 4.Blood vessels 5.All of these

33. In Ehlers-Danlos syndrome type I what protein is abnormal? 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Hemoglobin 2.Collagen 3.Histamine 4.Fibrinogen 5.None of these

34. What did Michael P. have to start eating? 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Apples 2.Collard Greens 3.Fatty acids 4.Bananas 5.Nucleotides

36. The slide you just saw is: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Loose connective tissue 2.Dense connective tissue 3.Cartilage 4.Compact bone 5.blood

38. That slide was: 1234567891011121314151617181920 2122232425262728293031323334353637383940 41424344454647484950 1.Loose connective 2.Dense connective 3.Cartilage 4.Bone 5.Smooth muscle