1. 2003-2004 Review of Anticoagulants, Thrombolytics and Anti-platelet Drugs 3 November 2015 5:19 AM

2. Abciximab Antiplatelet Anti-GPIIb/IIIa receptor antibody

3. Adalimumab TNF inhibitor Anti-TNF antibody Used in rheumatoid arthritis

4. Allopurinol Antigout Antineoplastic (supporting agent) Folic acid analogue Xanthine oxidase inhibitor

5. Aminocaproic acid (EACA) Procoagulant Inhibitor of plasminogen activation (decreases fibrinolysis)

6. Anistreplase Thrombolytic Streptokinase + plasminogen

7. Aprotinin Procoagulant Fibrinolytic inhibitor Serine protease inhibitor (“serpin”) Streptokinase inhibitor

8. Argatroban Anticoagulant Direct thrombin inhibitor

9. Aspirin (Acetylsalicylic acid, ASA) NSAID (acetylsalicylate) Analgesic, Anti-inflammatory Antipyretic, Antiplatelet Irreversible cyclooxygenase inhibitor

10. Atorvastatin Antihyperlipidemic HMG-CoA reductase inhibitor

11. Auranofin Disease modifying anti-rheumatic drug (DMARD) Gold salt Oral

12. Aurothioglucose Disease modifying anti-rheumatic drug (DMARD) Gold salt Parenteral

13. Balsalazide NSAID (salicylate) Treatment of IBD

14. Beclomethasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled

15. Betamethasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation

16. Bivalirudin Anticoagulant Direct thrombin inhibitor

17. Bradykinin Inflammatory mediator Plasma, hypotension, pain

18. Budesonide Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled OR treatment of IBD

19. C3a, C5a Inflammatory mediators Anaphylatoxins Low molecular weight complement cleavage products

20. Celecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

21. Cholestyramine Antihyperlipidemic Bile acid binding resin (BABR)

22. Clofibrate Antihyperlipidemic Lipoprotein lipase activator

23. Clopidogrel Antiplatelet ADP receptor antagonist

24. Colchicine Antigout only Anti-inflammatory Microtubule inhibitor

25. Colestipol Antihyperlipidemic Bile acid binding resin (BABR)

26. Cortisol (Hydrocortisone) Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid

27. Cromolyn sodium Mast cell stabilizer Inhibits release of mast cell mediators Used prophylactically in asthma

28. Dalteparin Anticoagulant LMW Heparin ATIII activator

29. Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Antiemetic Anti-inflammatory steroid Not by inhalation

30. Diflunisal NSAID Analgesic, Anti-inflammatory Antipyretic Cyclooxygenase inhibitor

31. Dipyridamole Antiplatelet Phosphodiesterase inhibitor (increases cAMP)

32. Drotrecogin alfa (Activated Protein C) Anticoagulant Many actions Treatment for septic shock

33. Enoxaparin Anticoagulant LMW Heparin ATIII activator

34. Eptifibatide Antiplatelet GPIIb/IIIa antagonist

35. Erythropoietin (EPO) Cytokine Primary regulator of RBC synthesis

36. Etanercept TNF inhibitor Tumor necrosis factor receptor + F c portion of IgG Used in rheumatoid arthritis

37. Ezitimibe Antihyperlipidemic Cholesterol absorption inhibitor

38. Fenofibrate Antihyperlipidemic Lipoprotein lipase activator

39. Flunisolide Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled

40. Fluticasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled

41. Fluvastatin Antihyperlipidemic HMG-CoA Reductase Inhibitor

42. Gemfibrozil Antihyperlipidemic Lipoprotein lipase activator

43. Gold salts Disease modifying anti-rheumatic drugs (DMARD) auranofin, aurothioglucose

44. Granulocyte-Colony Stimulating Factor (G-CSF) Cytokine Granulocyte synthesis stimulator

45. Granulocyte/Monocyte-Colony Stimulating Factor (GM-CSF) Cytokine WBC (granulocytes and monocyte) synthesis stimulator

46. Heparin Anticoagulant ATIII activator

47. Hirudin Anticoagulant Direct thrombin inhibitor (DTI)

48. Histamine Inflammatory mediator Stored in mast cells and basophils

49. Hydrocortisone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid

50. Hydroxychloroquine Disease modifying anti-rheumatic drug (DMARD)

51. 4-Hydroxycoumarin Oral anticoagulant Vitamin K synthesis inhibitor

52. Ibuprofen NSAID Analgesic, Anti-inflammatory Antipyretic Reversible cyclooxygenase inhibitor

53. Indomethacin NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor Tocolytic Uterine relaxant

54. Infliximab TNF inhibitor Anti-TNF monoclonal antibody Treatment of IBD

55. Interferon alpha Antiviral for hepatitis Antineoplastic Cytokine Anti-angiogenesis

56. Interleukin 2 Cytokine Antineoplastic

57. Interleukin 11 Cytokine Antineoplastic (supporting agent)

58. Kallidin Inflammatory mediator Plasma, hypotension, pain

59. Ketoprofen NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

60. Lepirudin Anticoagulant Direct thrombin inhibitor (DTI)

61. Leukotriene B 4 (LTB 4 ) Inflammatory mediator Lipoxygenase product of arachidonate metabolism Chemotactic

62. Leukotrienes C 4, D 4, E 4 (LTC 4, LTD 4, LTE 4 ) Inflammatory mediators Cysteinyl leukotrienes Peptidyl leukotrienes SRS-A Lipoxygenase products of arachidonate metabolism

63. Lovastatin Antihyperlipidemic HMG-CoA reductase inhibitor

64. Meclofenamate NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

65. Mesalamine (5-ASA) NSAID (salicylate) Treatment of IBD

66. Methylprednisolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation

67. Montelukast Leukotriene inhibitor LTR1 and LTD4 antagonist Asthma treatment

68. Naproxen NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

69. Nedocromil Mast cell stabilizer Inhibits release of mast cell mediators Used prophylactically in asthma

70. Nicotinic acid Antihyperlipidemic Inhibition of VLDL secretion (?)

71. Non-steroidal Anti-inflammatory Drugs (NSAIDs) Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitors

72. Olsalazine NSAID (salicylate) Treatment of IBD

73. Phytonadione Vitamin K Warfarin antagonist

74. Piroxicam NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

75. Platelet Activating Factor (PAF) Inflammatory mediator Lipid Hypotensive

76. Pravastatin Antihyperlipidemic HMG-CoA reductase inhibitor

77. Prednisone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory Not by inhalation

78. Probenecid Uricosuric Adjunct in penicillin therapy

79. Probucol Antihyperlipidemic LDL oxidation inhibitor

80. Prostaglandin E 2 (PGE 2 ) Dinoprostone (Dinoprost) Oxytocic prostaglandin Inflammatory mediator Cyclooxygenase product of arachidonate metabolism Uterine stimulant Cervical ripener

81. Prostaglandin F 2 (PGF 2 ) Inflammatory mediator Cyclooxygenase product of arachidonate metabolism

82. Prostaglandin I 2 (PGI 2 ) Inflammatory mediator Inhibits platelet aggregation Cyclooxygenase product of arachidonate metabolism Prostacyclin

83. Protamine Sulfate Heparin antagonist

84. Rofecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

85. Simvastatin Antihyperlipidemic HMG-CoA reductase inhibitor

86. Streptokinase Thrombolytic

87. Rofecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

88. Sulfasalazine Disease modifying anti-rheumatic drug (DMARD) Metabolized to sulfonamide + salicylate (NSAID) Treatment of IBD

89. Sulfinpyrazone Uricosuric Anti-gout

90. Sulindac NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

91. Thrombopoietin Cytokine Platelet synthesis stimulator

92. Thromboxane A 2 (TXA 2 ) Autacoid Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

93. Ticlopidine Antiplatelet ADP receptor antagonist

94. Tissue plasminogen activators Thrombolytics alteplase, reteplase, tenecteplase

95. Triamcinolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled

96. Tumor necrosis factor  Cytokine Antineoplastic

97. Urokinase Thrombolytic

98. Warfarin Anticoagulant Vitamin K synthesis inhibitor

99. Zafirlukast Leukotriene inhibitor LTR 1 and LTD 4 antagonist Asthma treatment

100. Zileuton Leukotriene inhibitor 5-lipoxygenase inhibitor Used in asthma