1. 1 Ancylostomiasis 钩虫病 08 动医 2 班 Speaker ：赖华英 Partner ：余剑敏 罗宇声 利 钊 覃捷梅

2. 2 Ancyloslomiasis钩虫病 Epidemiology流行病学 Diagnosis诊断 Control控制 References 参考书 Life cycle 生活周期 Morphology 形态学 Introduction引言 Lesions病变 Symptoms 症状

3. 3 1 Introduction 钩口科（ Ancylostomatidae ） 1,Ancylostoma caninum 犬钩口线虫 2,Unciaria stenocephala 狭头弯口线虫 3, Ancylostomiasis braziliense 巴西钩口线虫 4, Ancylostomiasis ceylanicum 锡兰钩口线虫 5,Necator americanus 美洲板口线虫 (Human)

4. 4 2 Morphology The oval-shaped( 椭圆的 ) egg of Ancylostoma caninum 65μm×37μm, obtuse （钝的） in the ends, colourless and translucent （半透明的）. The egg of 4-cell stage

5. 5 If the sample was placed for a long time, the egg of 4-cell stage will change into 8-cells stage or mulberry-shaped( 桑葚状 ). The egg of 8-cell stageThe mulberry-like egg

6. 6 Ancylostoma caninumUnciaria stenocephala cutting plates with teeth Buccal capsule Copulatory bursa Side of female tail

7. 7 Site of infection colourmalefemaleThe color/shape/size of egg Buccal capsuel Ancylostoma caninum Small intestine yellowish white 10~1 2mm 14~16 mm beige/oval- shaped/55~76um×34~45 um The main differential diagnosis is the cutting plate Unciaria stenocephala Small intestine yellow 5~8.5 mm 7~10m m -/oval- shaped/65~80um×40~50 um

8. 8 3 Life cycle Direct life cycle Infective stage ： filariform( 丝状 蚴 ) Site of infection ： small intestine Host ： dog and cat Diagnostic stage ： egg

9. 9 Three Routes Transcolostral: Infected bitch nurse offspring the larvae Infection through ingestion:gut wall circulation liver heart lung alveoli coughed up and swallowed small intestine Infection through the skin:skin circulation heart lung alveoli coughed up and swallowed small intestine

10. 10 人钩虫的生活史 rhabtidiform larva filariform larva egg L1 L2 L3 morula heart lung In the intestine

11. 11 3 Life cycle

12. 12 4 Epidemiology Ancylostoma caninum is one of the most common parasites in dogs and is widespread in the world. Routes of infection: peroral infection( 经口 传染 ) 、 by the skin( 经皮肤 ) 、 via the placental( 通过胎盘 ) or colostrum ( 初乳 ) This disease occurs most in summer.

13. 13 5 Signs or Symptoms 1.Acute type: emaciation( 消瘦 ) 、 pale mucosa( 黏膜苍白 ) 、 decreased appetite( 食欲减退 ) 、 vomiting( 呕 吐 ) 、 gastricism( 消化障碍 ) 、 diarrhea( 下痢 ) 、 constipation( 便秘 ) 、 bloody stool ( 粪便带 血 ) 、 anaemia( 贫血 )

14. 14 2.Chronic type: light anaemia 、 malnutrition( 营养不 良 ) 、 gastrointestinal dysfunction( 胃 肠功能紊乱 ) 3.Uncinarial dermatitis( 钩虫性皮炎 )

15. 15 6 Lesions Hemorrhage( 出血 ) 、 ulcer on intestinal mucosa Dermatitis( 皮炎 ) Pneumorrhagia( 肺出血 ) and pneumonia( 肺 炎 )

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18. 18 7 Diagnosis 1.Direct smear 2.Flotation method 3.Fecal culture 4.IFA

19. 19 8 Control 1. The treatment of the dogs and cats Drug of choice is dimphenol( 二碘硝基酚 ). Other effective drugs include levamisole ( 左旋咪唑 ), albendazole( 丙硫 咪唑 ), ivermectin( 伊维菌素 ).

20. 20 2. Comprehensive prevention (1) Treating sick dogs and cats in time and avoid feeding dogs and cats with raw foods. (2) Keep the dogtery( 犬舍 ) dry, feces management （粪便处理 ), Kill eggs by boiling water and solarization. (3) Deratization( 灭鼠 ).

21. 21 9 References 【 1 】 韦华，杨玉荣. 宠物犬犬钩虫的调查及 生活史各期形态观察 [J]. 中国人兽共患病 学报.2006,22(8):789-791 【 2 】 李国清. 兽医寄生虫（双语版） [M] ．北 京：中国农业出版社， 2006,339-342

22. 22 Thank you ！