1. Intra-ocular Injection Client: Barbra Blodi, M.D. Advisor: Paul Thompson Group Members: Mike Swift, Rajit Chakravarty, Mike Hallam, Anthony Nelson

2. Overview Background Description of product specification Design Alternatives Proposed Solution Future Plans Conclusion

3. Background Macula –Macular Degeneration Current Treatment –Description –Problems

4. The Macula

5. Current Treatment

6. Product Specifications Slow injection rate One handed grip and actuation Work with existing 1 cc syringes Reusability Injection control Stoppable Accuracy

7. Design Alternatives Hydraulic pressure pump Spring operated Reusable case mechanism

8. Hydraulic pressure Pros: More control over injection Vary injection speed Emergency stop capabilities Cons: Non-reusable Extensive syringe modifications Difficult to administer accurate injections

9. Spring operated Pros: Increases injection accuracy Slow, steady administration Cons: Non Reusable Extensive modifications

10. Reusable Case Pros: Reusable Increased injection accuracy Stoppable Cons: Potential complications with catching mechanism Size constraints for catching mechanism

11. Case Prototype

12. Proposed Solution Modified Reusable Case Mechanism Ergonomic Design Compatible with existing syringes Easily reusable One handed grip and actuation

13. Proposed Solution High level of injection control Stoppable and restartable Accuracy of injection volume

14. Future Plans Develop prototype model of modified design Real-life prototype testing on cow eyes Further modifications on design after testing

15. Conclusions Problem: Modify syringe to allow single clinician to perform injections Proposed Solution: Modified Reusable Case Mechanism Future work: Build workable prototype of new design Begin prototype testing