1. Tomotherapy Radiation Treatment for Cancer 3-D Imaging of Target Tissue Helical Delivery Pattern Intensity Modulation Radiotherapy (IMRT) -Multileaf Collimator (MLC) Radiation Concentrates on Moving Target Tissue

2. Motivations When Patient Breaths Target Tissue Moves Patient Needs to Breath in Steady Repeatable Pattern Patient Needs to Practice the Breathing at Home Current Devices are Large, Expensive and Hard to Use

3. Client Requirements Patient Must Practice Breathing Pattern at Home Display of Patients Breathing Pattern and Guiding Cycle Device Must be Small and Portable Device Must be User Friendly

4. Inside the Project Box

5. Pocket PC with PCMCIA Cradle

6. Screen Shots of Client and Patient Program

7. Hardware ABS plastic project box (4” x 1.5” x 2”) Linear Potentiometer with 3” of travel 9V Battery SPDT Toggle Switch Adjustable Chest Strap with Buckle NI DAQ-6024E A/D Converter (PCMCIA Style) Male/Female Electrical Connectors

8. Hardware Project box attached to chest strap with rivets Tension of chest strap increased with elastic band Displacement limited by slack on chest strap Output voltage 0V-9V based on string displacement

9. Software Programmed in LabView Signal sampled from National Instrument Data Acquisition Card Sampling rate can be adjusted accordingly 2 Programs: Client: For obtaining the guiding cycle Patient: Display real-time breathing and guiding cycle simultaneously

10. Software Currently program can only read the guiding cycle once Need to repeat guiding cycle continuously Improve way of displaying guiding cycle and real-time breathing patterns (i.e. waveform graph)

11. Future Work Scale design down to portable PDA operated device PDA must be fitted with PCMCIA cradle for DAQ card interface LabVIEW 7.0 PDA module supports applications on PDA Create custom digital cable to replace bulky digital acquisition board

12. Future Work Eventually design device for use in the tomotherapy machine Video goggles and new software for display to patient while in tomotherapy machine All materials used analyzed for safety in high radiation environment Calculate attenuation and compensate during treatment Human subjects approval

13. Future Work Plan to continue work as BME 400 Capstone design project Wish to refine and completely finish design Disclose for patent over summer Present finalized design to client and production company