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Chromosomes and Cell Reproduction
Chapter 6 & 7
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I. Chromosomes Chromosome- made of 2 exact copies of DNA coiled around proteins (*this is after replication but before cell division) Chromatid- each copy of the DNA on a chromosome Centromere- place where the chromatids attach to make a chromosome Genes- Segments of DNA on a chromosome that code for a specific protein/trait
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*Draw a chromosome and label chromatids, centromere and gene
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II. Chromosome Number Each human somatic cell (body cell) has 2 copies of 23 different chromosomes for a total of 46 chromosomes We inherit 1 of each chromosome from mom and 1 from dad Homologous Chromosomes- similar in size, shape and genetic content
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D. Diploid cells- contain 2 sets of chromosomes, all somatic cells are diploid
(ex. Somatic cells in humans have a total of 46 chromosomes) E. Haploid Cells- contain only 1 set of chromosomes, only gametes can be haploid (ex. Gametes in humans have 23 chromosomes)
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III. Karyotypes A picture of the chromosomes of an organism arranged by size Used to examine an individuals chromosomes: Karyotypes can determine only 2 things about the organism: Sex of individual Any abnormalities in the chromosomes (number or shape
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C. Humans have 1 pair of sex chromosomes and 22 pairs of autosomal chromosomes (non sex chromosomes)
D. Sex Chromosomes- XX= Female XY= Male (the sex chromosomes are the last pair of chromosomes shown in a karyotype)
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Trisomy – when there is three of a certain chromosome instead of the normal 2
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IV. Cell Cycle G1 Phase- period of cell growth
S Phase- when DNA replication occurs G2 Phase- cell growth and preparation for mitosis Mitosis- division of the nucleus Cytokinesis- division of the cytoplasm
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Cell Cycle Animations http://www.cellsalive.com/cell_cycle.htm
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V. Mitosis The division of the nucleus in somatic cells
Chromosomes have replicated prior to the start of mitosis Produces 2 identical daughter cells 4 phases
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Prophase- chromatin coils into chromosomes Nuclear envelope dissolves Spindle fibers form
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2. Metaphase (middle) Chromosomes line up in the middle of the cell Centrioles move to opposite poles Spindle fibers attach to chromosomes
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3. Anaphase (apart) Spindle fibers shorten and pull chromatids toward opposite poles
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4. Telophase (opposite of prophase)
Nuclear envelope forms around chromatids Chromatids uncoil Cleavage is formed Spindle fibers dissolve
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Cytoplasm is divided in half
E. Cytokinesis Occurs after Mitosis Cytoplasm is divided in half Cell membrane encloses each cell **New cells are now in interphase and the cell cycle starts over.
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Mitosis Animation http://iknow.net/cell_div_education.html
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VI. Meiosis Two divisions of the nucleus
Results in the formation of 4 gametes (egg, sperm) Halves the number of chromosomes (in humans from 46 to 23)
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Stages of Meiosis I 1.*Prophase I- crossing over occurs, (portions of one chromosome are broken and exchanged with portions of the other homologue)**results in genetic variability 2. Metaphase I- homologous chromosome pair up together at the equator 3. Anaphase I- centromeres do not divide 4. Telophase I and Cytokinesis
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Meiosis II 1. Prophase II 2. Metaphase II 3. Anaphase II
4. Telophase II & Cytokinesis Interphase P 1 M 1 A 1 T1 & C P 2 M 2 A 2 T 2 Cytokinesis
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Females- called oogenesis, forms 1 ovum and 3 polar bodies
Males- called spermatogenesis, forms 4 sperm cells
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http://www. biologyexams4u
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Meiosis Animations Meiosis Animation Meiosis Square Dance Video
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