1. Work Group 3 Life Sciences and Health Challenges of optical technologies in Life Sciences and Health Linear, mostly technology-driven approach Little exchange between optical technologies, medicine and life sciences, and even within optical technologies Obstacles for companies: Little or no knowledge about users’ needs and potential of photonic technologies Solution: Paradigm shift introduced by Biophotonics Evolving from a linear, technology-driven approach towards a holistic, user- and market-oriented approach by involving the end-user Topic of WG meeting: Putting Biophotonics into clinic

2. Work Group 3 Life Sciences and Health Prof. Dr. Katarina Svanberg: The Doctor's View on Photonics - Clinical Challenges and Technical Possibilities Prof. Dr. Hans-Peter Berlien: Biophotonic - The Physicians Perspective Prof. Dr. Axel Niendorf: Pathology - a Chance for Biophotonics Dr. Martin Kaatz: Fiber net work of skin by multiphoton laser scanning tomography - qualitative and quantitative features Putting Biophotonics into clinic

3. Work Group 3 Life Sciences and Health Résumé (1):  Breaking down barriers between the different disciplines participating in Biophotonics research  Fundamentals of light / biological matter interaction for diagnostics and especially for therapy  Early diagnostics is the paramount factor for prognosis (separate inflammation from early cancer and precancer)  Minimize biopsies by performing optical biopsies (Elastic light scattering, Fluorescence, Raman,…)  Advanced spectroscopic techniques for a more precise tumor borders detection  Diagnostics (e.g. staging and grading of cancer) cannot be tackled by one technique alone → Multimodal Approaches are necessary! Putting Biophotonics into clinic

4. Work Group 3 Life Sciences and Health Résumé (2):  Advanced imaging and functional imaging methods (with new Markers)  Image analysis  Advanced Endoscopy combined e.g. with OCT  Cross-disciplinary settings (technology pull, getting in close contact with the health community (Health))  The entire medical process needs to be optimized and standardized (sampling, diagnostics and therapy) Putting Biophotonics into clinic

5. Work Group 3 Life Sciences and Health Résumé (3):  Development and integration of realistic clinical systems:  High performance light sources  High resolution detector systems  User-friendly software  Robustness for mobility  Realistic price (GP office use; less than 8000 Euro) To do list:  Working on the Strategic Research agenda  Getting into contact with Health  Defining projects with ETP nanomedicine Putting Biophotonics into clinic