1. Breast Ovarian Hereditary Breast & Ovarian Cancer Knowing one’s family medical history can be life-saving.

2. Hereditary Breast and Ovarian Cancer

3. GENES: BRCA 1 & BRCA 2 BRCA 1 52% UNCERTAIN16%  Hereditary

4. Looking deeper into the DNA

5. Hereditary = Born with the mutation Sporadic = damage occurs after birth MUTATION = increased risk for cancer Alcohol /poor Diet / Tobacco Weak immune system Obesity/ Lifestyle/Hormones Environment/Getting older

6. Consider…

7. How is a mutated gene passed on?      

8. Cancer risks of BRCA 1 / 2 carriers compared to General Population

9. Genetic Material Sampling Blood Saliva (Buccal cells)

10. higher risk Having the mutation does not necessarily mean that you will develop cancer. It means you are at a higher risk for developing cancer compared to someone who does not have the mutation.

12. Possible Recommendations: If there is a mutation [+] Risk-reducing mastectomy Risk-reducing removal of ovaries and fallopian tubes Use of medications known to minimize risk: Tamoxifen or Raloxifene Managing the risk