1. 11 year old castrated male Labrador Retriever

2. History  Presented to NCSU Emergency Clinic on 3-19- 07 for blood dripping from penis  Blood had been dripping from penis since Christmas 2006  Started on 3 week course of doxycycline for a presumed UTI, but clinical signs resumed shortly thereafter  Another course of doxycycline was prescribed for 6-8 weeks  When he presented here he was having dysuria/stranguria

3.  Owner states that urine stream is always yellow but clots of blood will pass in the stream  rDVM felt that the bulbourethral glands were enlarged and that there was a swelling caudal to the os penis  No other relative history

4.  Relative Findings  Lungs auscult clearly with increased bronchvesicular sounds bilaterally  Prostate palpates small and symmetrical on rectal palpation  Extrusion of penis reveal no gross abnormalities except a blood clot on the urethral orifice  Caudal to the os penis a plum sized firm mass seems adhered to underlying structures  CBC – WNL, Chem panel – no significant findings,  Urinalysis USG 1.019, ph 6, 2+ proteinuria, 0-5 WBC/hpf, 0-5 RBC/hpf, culture no growth

11.  Right medial iliac lymph node  Low cellularity – small lymphocytes  Penile mass aspirate  Neoplastic cells most consistent with carcinoma but a poorly differentiated sarcoma could not be ruled out

12.  Thoracic radiographs  Possible pulmonary nodule in left caudal lung lobe  Abdominal radiographs  Mineralized soft tissue mass associated with caudal os penis  Flouroscopy  Confirmed presence of pulmonary nodule  CT  Two soft tissue nodules in left caudal lung lobe  Soft tissue mass at caudal os penis, potentially of urethral or os penis origin  Enlarged medial iliac lymph node

13.  Mass noted 10.5 cm from the distal end of the uretha and extended for 2 cm proximally  Pinch biopsies taken  Dysplastic transitional epithelium vs transitional cell carcinoma  Bladder normal except for dilated urethral orifices

16.  Scrotal urethrostomy  Penis amputation  Histopathology  Hemangiosarcoma with clean margins  Flash is going to have follow up with Oncology Services