1. Chapter 40 ~ An Introduction to Animal Structure and Function

2. Tissues: groups of cells with a common structure and function (4 types) Anatomy: structure Physiology: function 1- Epithelial: outside of body and lines organs and cavities; held together by tight junctions basement membrane: dense mat of extracellular matrix

3. Tissues Simple: single layer of cells Stratified: multiple tiers of cells Cuboidal (like dice) Columnar (like bricks on end) Squamous (like floor tiles) mucous membrane

4. Tissues, II 2- Connective: bind and support other tissues; scattered cells through matrix; 3 kinds: –A-Collagenous fibers (collagen protein) –B-Elastic fibers (elastin protein) –C-Reticular fibers (thin branched collagen fibers) Loose connective tissue: binds epithelia to underlying tissue; holds organs –Fibroblasts- secretes extracellular proteins 2-Macrophages- amoeboid WBC’s; phagocytosis –Adipose tissue- fat storage; insulation Fibrous connective tissue: parallel bundles of cells –Tendons- muscles to bones –Ligaments- bones to bones; joints (BOBOLI)

5. Cartilage: collagen in a rubbery matrix (chondroitin); flexible support Bone: mineralized tissue by osteoblasts Blood: liquid plasma matrix; erythrocytes (RBC’s) carry O2; leukocytes (WBC’s) immunity

7. Tissues, III 3-Nervous: senses stimuli and transmits signals from 1 part of the animal to another Neuron: functional unit that transmits impulses Dendrites: transmit impulses from tips to rest of neuron Axons: transmit impulses toward another neuron or effector

8. Tissues, IV 4- Muscle: capable of contracting when stimulated by nerve impulses; myofibrils composed of proteins actin and myosin; 3 types: A- Skeletal: voluntary movement (striated) B- Cardiac: contractile wall of heart (branched striated) C- Smooth: involuntary activities (no striations)

9. Organ systems Organ: organization of tissues Mesentaries: suspension of organs (connective tissue) Thoracic cavity (lungs and heart) Abdominal cavity (intestines) Diaphragm (respiration) Organ systems…... How many can you come up with? Digestive-food processing Circulatory-internal distribution Respiratory-gas exchange Immune/Lymphatic-defense Excretory-waste disposal; osmoregulation Endocrine-coordination of body activities Reproductive-reproduction Nervous-detection of stimuli Integumentary-protection Skeletal-support; protection Muscular-movement; locomotion

10. Internal regulation Interstitial fluid: internal fluid environment of vertebrates; exchanges nutrients and wastes Homeostasis: “steady state” or internal balance Negative feedback: change in a physiological variable that is being monitored triggers a response that counteracts the initial fluctuation; i.e., body temperature Positive feedback: physiological control mechanism in which a change in some variable triggers mechanisms that amplify the change; i.e., uterine contractions at childbirth

11. Metabolism: sum of all energy- requiring biochemical reactions Catabolic processes of cellular respiration Calorie; kilocalorie/C Endotherms: bodies warmed by metabolic heat Ectotherms: bodies warmed by environment Basal Metabolic Rate (BMR): minimal rate powering basic functions of life (endotherms) Standard Metabolic Rate (SMR): minimal rate powering basic functions of life (ectotherms)

12. Homeostasis The underlying principle of physiology is homeostasis Homeostasis is the ability to maintain a relatively stable internal environment in an ever-changing outside world The internal environment of the body is in a dynamic state of equilibrium (dynamic constancy) Chemical, thermal, and neural factors interact to maintain homeostasis Loss of homeostasis results in disease or death

13. Examples of Homeostatically Regulated Variables Body Temperature Blood Composition (ions, sugars, proteins) Concentrations of O 2 and CO 2 in the blood Acid-Base balance (pH) Blood osmolarity Blood pressure, cardiac output, cardiac rate Respiratory rate and depth Secretions of endocrine glands Rate of chemical reactions intracellularly

14. Set Point and Standards Values of variables fluctuate around the set point to establish a normal range of values. Set point –The ideal normal value of a variable. What is the set point for body temperature? For blood sugar levels? For blood pH? Note: the setpoint for some variables may be ‘reset’ -that is, physiologically raised or lowered (e.g., BP)

15. Homeostatic Control Mechanisms The variable produces a change in the body –E.g. Increase in blood sugar levels or body temperature The three interdependent components of control mechanisms are: –Receptor – monitors the environments and responds to changes (stimuli) –Control center – determines the set point at which the variable is maintained –Effector – structures that provide the means to respond to the stimulus and restore the variables to the optimal physiological range.

16. Interpret the arrows in textbook’s flow charts as “leads to” or “causes.” (e.g., decreased room temperature causes increased heat loss from the body, which leads to a decrease in body temperature, etc.)

17. Negative Feedback

18. Example of Negative Feedback