1. BIOLOGY CONCEPTS & CONNECTIONS Fourth Edition Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Neil A. Campbell Jane B. Reece Lawrence G. Mitchell Martha R. Taylor From PowerPoint ® Lectures for Biology: Concepts & Connections CHAPTER 6 The Molecules of Cells Modules 3.4 – 3.10

2. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings A carbon atom forms four covalent bonds –It can join with other carbon atoms to make chains or rings 3.1 Life’s molecular diversity is based on the properties of carbon Figure 3.1, top part Structural formula Ball-and-stick model Space-filling model Methane The 4 single bonds of carbon point to the corners of a tetrahedron.

3. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Most of the large molecules in living things are macromolecules called polymers –Macromolecules include carbohydrates, lipids, proteins, and nucleic acids –Polymers are long chains of smaller molecular units called monomers (building blocks) –A huge number of different polymers can be made from a small number of monomers 3.3 Making Polymers

4. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Cells link monomers to form polymers by dehydration synthesis: the joining of two monomers to make a polymer by removing water 123 Unlinked monomer Removal of water molecule 1234 Longer polymer Figure 3.3A Short polymer

5. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Polymers are broken down to monomers by the reverse process, hydrolysis: breaking down polymers into monomers by adding water Coating of capture strand 123 Addition of water molecule 123 Figure 3.3B 4

6. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Carbohydrates are a class of macromolecules –They range from small sugars to large polysaccharides –Monomers (building blocks) of carbs are monosaccharides (simple sugars) –Polymers (larger molecules) of carbs are polysaccharides (long polymers of many monomers) CARBOHYDRATES

7. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Monosaccharides are single-unit sugars Each molecule contains hydroxyl groups (-OH) and a carbonyl group (CO) Monosaccharides are the fuels for cellular work 3.4 Monosaccharides are the simplest carbohydrates Figure 3.4A

8. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings The monosaccharides glucose and fructose are isomers –They contain the same atoms but in different arrangements GlucoseFructose Figure 3.4B

9. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Monosaccharides can join to form disaccharides, such as sucrose (table sugar) and maltose (brewing sugar) 3.5 Cells link single sugars to form disaccharides Glucose Maltose Figure 3.5 Sucrose

10. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Polysaccharides: large molecules are polymers of hundreds or thousands of monosaccharides linked by dehydration synthesis You need to know 4 polysaccharides… 3.7 Polysaccharides are long chains of sugar units

11. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Starch (used for storage in plant roots) and glycogen (how animals store sugar) Cellulose is a polysaccharide in plant cell walls Chitin is polysaccharide used by insects and other animals to make shells and exoskeletons Figure 3.7 Starch granules in potato tuber cells Glucose monomer STARCH GLYCOGEN CELLULOSE Glycogen granules in muscle tissue Cellulose fibrils in a plant cell wall Cellulose molecules

12. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Review Carbs Uses: energy storage, contain C, H, and O Monomers=Monosaccharides (glucose and fructose) Polymers=Polysaccharides (starch, glycogen, cellulose, chitin) Examples: Bread, pasta, potatoes, fruits and veggies, rice

13. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Lipids include fats, triglycerides, oils, waxes, and steroids and are used for energy storage These compounds are composed largely of carbon and hydrogen –They are grouped together because they do not mix with water (hydrophobic) 3.8 Lipids Figure 3.8A

14. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Fats are lipids whose main function is energy storage –They are also called triglycerides A triglyceride molecule consists of one glycerol molecule linked to three fatty acids tails Figure 3.8B Fatty acid

15. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings The fatty acids of unsaturated fats (plant oils) contain double bonds –These prevent them from solidifying at room temperature (olive oil, vegetable oil) Saturated fats (lard) lack double bonds-are saturated with hydrogens –They are solid at room temperature (butter, lard, crisco) Figure 3.8C

16. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Phospholipids are a major component of cell membranes Waxes form waterproof coatings Steroids are often hormones 3.9 Phospholipids, waxes, and steroids are lipids with a variety of functions Figure 3.9

17. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Review Lipids Uses: Energy storage, cell membrane components Made of C, H Monomers: glycerol head and 3 fatty acids tails Polymers: triglycerides Examples: fats (triglycerides), oils, waxes, phospholipids, and steroids; butter, crisco, ice cream, dairy

18. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Anabolic steroids are usually synthetic variants of testosterone Use of these substances can cause serious health problems 3.10 Connection: Anabolic steroids and related substances pose health risks Figure 3.10