1. 1QQ # 2 for GR’s Friday Classes

2. 1QQ # 2 for 10:30 For the negative feedback loop for thermoregulation
Name on top edge, back side of paper
Answer on the blank side of paper. If the statement is true, mark it true.
If false, replace the underlined word to make it a true statement.
For the negative feedback loop for thermoregulation
The hypothalmus is an afferent pathway.
Somatic nerves are the efferent pathway to sweat glands.
Skeletal muscle tone would be increased as a response to a drop in core body temperature
Peripheral sensory nerves are the afferent pathway that convey skin temperature information
Cutaneous arterioles would dilate in response to a drop in core body temperature.

3. 1QQ # 2 for 11:30 For the negative feedback loop for thermoregulation
Name on top edge, back side of paper
Answer on the blank side of paper. If the statement is true, mark it true.
If false, replace the underlined word to make it a true statement.
For the negative feedback loop for thermoregulation
The hypothalmus is an efferent pathway.
Somatic nerves are the efferent pathway to sweat glands.
Skeletal muscle tone would be increased as a response to a drop in core body temperature
Peripheral sensory nerves are the efferent pathway that convey skin temperature information
Cutaneous arterioles would constrict in response to a drop in core body temperature.

4. “Andro” paper
Read the paper.  Before coming to lab, write a paragraph in which you 1) identify the major objectives of the paper (the most important questions it addresses), and 2) a concise summary of the most important findings presented in the paper. Bring this text with you to lab, ready to turn in to the lab instructor.

5. Flow diagram of a fever Explain “chills” at onset of a fever
Central & Peripheral Thermoreceptors
Explain “chills” at onset of a fever
Explain “sweat” when a fever “breaks”
How does Tylenol reduce a fever?
To reach new,
Higher set point

6. Acclimatization 1st day of training
Increase body temp….. Delayed sweating via negative feedback
After a week of training
Sweating precedes changes in core body temperature
and sweating is increased
And salt loss in sweat is minimized
Responses begin even before core temperature increases! Not just negative feedback.
Acclimatization

7. Acclimatization Classical learning (by experience)
Feedforward pathway: response begins before there is a change in the physiological variable
Intelligent system anticipates likely changes
Classical learning (by experience)
Minimizes fluctuations

8. 1. Brain function & 2. Heat loss mechanisms
Increase cell metabolism
Increase Body Temp.
Failure of
1. Brain function & 2. Heat loss mechanisms
Heat Stroke
Blood Pressure
Blood Q to brain
Excessive Sweating and
Cutaneous vasodilation
Sympathetic outflow
Disrupted function of neurons

9. Positive feedback Inherently unstable
Examples of Positive Feedback in Physiology
Heat stroke (diagrammed on previous slide)
formation of blood clot
menstrual cycling of female sex hormone concentrations
generation of action potentials in nerve fibers
uterine contractions during childbirth
Each of these examples terminate naturally (self limiting)