1. PowerPoint Slides for Chapter 2: Central Dogma by A. Malcolm Campbell, Laurie J. Heyer, & Christopher Paradise 2.1 How does DNA communicate information to the cell? Integrating Concepts in Biology Title Page Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

2. Biology Learning Objective Describe the three major types of RNA and their functions. ELSI Learning Objective Discriminate between jargon and literal uses of terms that can lead to misunderstandings about science. Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

3. Cells Are Assemble Molecules Opening Figure Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

4. Building Complexity from Simplicity Fig. 2.1 yolk albumin Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

5. Building Complexity from Simplicity Fig. 2.1 single cell Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

6. Building Complexity from Simplicity Fig. 2.1 Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

7. Choose your words carefully ELSI Fig. 2.1 Courtesy of Travis Mohrman,

8. Diversity of Cell Shape and Function Fig. 2.2 courtesy Kristian Peters and Elizabeth H. White

9. What does RNA do for cells? Fig. 2.3 courtesy Todd Eckdahl

10. Yeast RNA Separated by Size Fig. 2.3 courtesy Todd Eckdahl

11. Yeast RNA Separated by Size Fig. 2.3 What is the function of MW markers? courtesy Todd Eckdahl

12. Yeast RNA Separated by Size Fig. 2.3 What is this blob? courtesy Todd Eckdahl

13. Yeast RNA Separated by Size Fig. 2.3 What do you see in lanes 1 and 2? Any differences between the two? courtesy Todd Eckdahl

14. Yeast RNA Separated by Size Fig. 2.3 What’s this? courtesy Todd Eckdahl

15. Yeast RNA Separated by Size Fig. 2.3 What do you see in lanes 1 and 2? courtesy Todd Eckdahl

16. Yeast RNA Separated by Size Fig. 2.3 2 rRNA bands courtesy Todd Eckdahl

17. Ribosome Structure Fig. 2.4 Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

18. Ribosome Structure Fig. 2.4 Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

19. Ribosome Structure Fig. 2.4 Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

20. Ribosomes Produce Proteins Fig. 2.4 Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

21. Yeast RNA Separated by Size Fig. 2.3 What do you see in lanes 1 and 2? courtesy Todd Eckdahl

22. Figure 2.5A RNA and Amino Acids Interact modified from Chipchase and Birnstiel, 1963

23. Figure 2.5A RNA and Amino Acids Interact 2 sizes of rRNA modified from Chipchase and Birnstiel, 1963

24. Figure 2.5A RNA and Amino Acids Interact tRNA is very small modified from Chipchase and Birnstiel, 1963

25. Figure 2.5A RNA and Amino Acids Interact leucine is with tRNA modified from Chipchase and Birnstiel, 1963

26. Figure 2.5A tRNA and Amino Acids Interact tRNAs bring amino acids to ribosomes modified from Chipchase and Birnstiel, 1963

27. Figure 2.5A tRNA and Amino Acids Interact modified from Chipchase and Birnstiel, 1963

28. tRNA Structure Fig. 2.5B & C tRNA’s real shape nitrogen carbon oxygen phosphorous Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

29. tRNA Structure Fig. 2.5B & C anti-parallel base pairing tRNA’s shape ironed flat Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

30. tRNA Structure Fig. 2.5B & C tRNA’s functional parts Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

31. tRNA Structure Fig. 2.5B & C Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

32. tRNA Structure Fig. 2.5B & C Copyright © 2015 by AM Campbell, LJ Heyer, CJ Paradise. All rights reserved.

33. Yeast RNA Separated by Size Fig. 2.3 What do you see in lanes 1 and 2? courtesy Todd Eckdahl

34. Fig. 2.6 Which RNA tells ribosomes what to make? modified from Brenner et al. 1961

35. Size Fractionation of RNA Fig. 2.6 infect cells and add radioactive uracil modified from Brenner et al. 1961

36. Fig. 2.6 Two graphs in the same space. Size Fractionation of RNA modified from Brenner et al. 1961

37. Fig. 2.6 separate RNA based on size Size Fractionation of RNA modified from Brenner et al. 1961

38. Old and New RNA Fig. 2.6 all RNA by UV absorption modified from Brenner et al. 1961

39. rRNA Fig. 2.6 all RNA by UV absorption modified from Brenner et al. 1961

40. intact ribosomes Fig. 2.6 all RNA by UV absorption modified from Brenner et al. 1961

41. Only New RNA (viral) Fig. 2.6 radioactivity new RNA modified from Brenner et al. 1961

42. Only New RNA (viral) Fig. 2.6 radioactivity new RNA rRNA not new! modified from Brenner et al. 1961

43. mRNA tells ribosomes what to make Fig. 2.6 modified from Brenner et al. 1961

44. Separation of Three RNAs Fig. 2.6 three major types of RNA rRNA mRNA tRNA + mRNA tRNA modified from Brenner et al. 1961

45. Yeast RNA Separated by Size Fig. 2.3 rRNA mRNA tRNA mRNA courtesy Todd Eckdahl