1. Genetics Really about growth and development……

2. Heredity Heredity is biological inheritance –The set of characteristics an organism inherits form its parents Genetics is the study of heredity

3. Gregor Mendel (1822-1884) Studied in Vienna Taught in a High School (Brno, in Czech Republic) Worked in a garden One of the first to study only one trait at a time One of the first to analyze his data systematically One of the first to use mathematics to analyze data Did about 30,000 experiments

4. Mendel in the garden The true breeding stock of plants –Always passes its traits to the next generation Reproduction in pea plants –Pollen, male sex cells –Ovum, female sex cells –Seed is produced for new plant –Normal process is self-pollination; one plant is the parent Cross fertilization, two plants as parents

5. Mendel in the garden Seven traits By limiting what traits he followed he could manage the data These traits are obvious, yes or no traits Look on page 310 of your textbook now

6. Mendel in the garden Crossing (short for cross fertilization) Crossed the pollen and eggs of two true breeding parents The result was always the trait of only one parent Look at page 310 again Understand the nomenclature P and F-1 generation

7. Mendel in the garden Crossing of the plants from F-1 If Mendel had not done this he would have made no discovery The trait of the parent that did not show up in F-1 appeared in ¼ of the F-2

8. Mendel in the garden Merkmal –Some indivisible unit determined which trait the plant displayed –This word is German for character –We call this a gene today (the unit that determines traits)

9. Mendel in the garden Alleles –Mendel figured each plant has two copies of each “character” –One from each parent –Today we say a gene has two alleles

10. Mendel’s Big Leap Dominant and recessive –Why does a plant with two characters for Tall (each plant has two copies) grow to the same height as a plant with one copy of Tall (each plant got one copy of Tall and one copy of short from the plant with two copies of short) Mendel called the copy (allele) for tall the dominant character, the copy for short was the recessive character. Today we use the same terminology

11. Out of the garden Phenotype and Genotype Phenotype is what you see when you look at an organism, phenotype of the plants is what Mendel was looking at Genotype is the genetic composition, genotype is what Mendel was hypothesizing when he talked about characters and copies of characters

12. Out of the garden Today we say that an organism with identical copies of the alleles for a trait is homozygous for that trait (TT or tt, for Tall and short) Organisms with a mixed pair of alleles are heterozygous for the trait (Tt for tall) In modern terms Mendel crossed two plants, one homozygous for Tall (TT) one homozygous for short (tt) and the offspring (F-1) were all heterozygous (Tt) yet were all Tall.

13. Out of the garden Segregation –Mendel figured out that the two copies of the characters must separate when the plant produced pollen and eggs Today we call this segregation of alleles –TT and tt crossed produce Tt –Tt and Tt crossed produce TT, Tt, Tt and tt

14. Out of the garden Independent assortment –Mendel followed two traits at the same cross –The offspring showed distinct ratios of the different combination so he reasoned that the characters behave independently

15. Mendel’s contributions Individual units called genes determine biological characteristics For each gene, an organism receives one allele from each parent. The alleles separate form each other (segregation) when the reproductive cells are formed If an organism inherits different alleles for some trait one allele may be dominant over the other Some genes segregate independently