1. Male Reproductive System Biology 2122

2. Introduction 1. Primary sex organ (gonads) are the testes 2. Testes produce sperm via ‘spermatogenesis’ – Meiosis 3. Sex hormones (androgens) – play vital roles in development and function of reproductive organs and sexual behavior – Testosterone

3. Reproductive Organs (sagittal view)

4. Scrotum and Testes 1. Scrotum – Function – Structure Dartos and Cremaster muscles 2. Testes – Function – Structure Tuica vaginalis and albuginea Semineferous tubules Rete testes Epididymis Ductus Deferens

5. Penis and Duct System 1. Penis Structure – Perineum; Glans Penis – Prepuce – Corpus spongiosum – Corpora cavernosa Crura 2. Epididymis – P.S. epithelium – 20 days – sperm 3. Ductus Deferens – Ampulla – Ejaculatory duct – P.S. Epithelium 4. Urethra – Prostatic; membranous; spongy

6. Seminiferous Tubules 1. Function – Produce Sperm Spermatogenesis 2. Structure – Spermatogonia – Interstitial Cells 3. Spermatogenesis – Meiosis – Spermatocytes to Spermatids – Sperm – Sustentacular Cells Sertoli cells

7. Meiosis and Mitosis

8. Mitosis and Meiosis

9. Spermatogenesis - AnimationAnimation

10. Development of Sperm Head Midpiece Flagella

11. Prostate and Semen 1. Prostate – Secretion – Function 2. Semen – Contents pH – Function – Prostaglandins – Relaxins – Amount

12. Horomonal Regulation (1). Hypothalamus, anterior pituitary and testes (brain-testicular axis) (2). Four events that occur – (1). Release of GnRH – (2). GnRH stimulate release of FSH and LH – (3). FSH and spermotogenesis Stimulates sertoli cells to release ABP – (4). LH binding to interstitial cells Interstitial cell-stimulating hormone

13. Hormonal Regulation 1.GnRH released 2.GnRH to pituitary cells 3.FSH and ABP 4.LH binding to interstitial cells 5.Testosterone levels rise 6.Testosterone enters the blood stream 7.Testosterone ‘feedback’ 8.Inhibin

14. Secondary Sex Characteristics (1). Induced in nonreproductive organs (testosterone) (2). Characteristics – Pubic, facial and axillary hairs – Larynx enlarges – Skin thickens, oily – Skeletal muscles (density; size and mass) – BMR increased (increases sex drive)