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HIFU Technology History ABLATHERM ® Device Treatment Ablatherm Ablatherm ® INTEGRATED IMAGING The The HIFU Treatment for Localized Prostate Cancer Exit.

Published byBlaze Hensley Modified over 9 years ago

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Presentation on theme: "HIFU Technology History ABLATHERM ® Device Treatment Ablatherm Ablatherm ® INTEGRATED IMAGING The The HIFU Treatment for Localized Prostate Cancer Exit."— Presentation transcript:

1 HIFU Technology History ABLATHERM ® Device Treatment Ablatherm Ablatherm ® INTEGRATED IMAGING The The HIFU Treatment for Localized Prostate Cancer Exit www.debenedetti1547.org

2 HIFU Technology History ABLATHERM ® Device Treatment www.ar

3 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

4 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

5 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

6 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

7 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

8 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

9 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

10 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

11 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

12 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

13 HIFU Technology History ABLATHERM ® Device Treatment The device The probe Robotized Placement Scanning 3D imaging Planning Firing phase Ultrasound Final aspect End Ablatherm® HIFU : step by step

14 HIFU Technology History ABLATHERM ® Device Treatment Ultrasound Waves Generation Plane transducer Ultrasound waves emission by transducer electro-mechanical vibrations Tissue motion Tissue heating Acoustical pressure +++ --- Physical Principle Treatment Description

15 HIFU Technology History ABLATHERM ® Device Treatment Focused transducer Emitting ultrasound waves Tissue heating Over 85°C Acoustical pressure Focused Ultrasound Waves Physical Principle Treatment Description

16 HIFU Technology History ABLATHERM ® Device Treatment Tissue Lesion Formation Thermal effects + Cavitation effects + Time exposure = Tissue lesion Temperature Simulation INSERM U 557 Temperature Simulation INSERM U 557 Thermal Dose Simulation INSERM U 557 Thermal Dose Simulation INSERM U 557 HIC Technology H IFU I NDUCED C AVITATION Physical Principle Treatment Description

17 HIFU Technology History ABLATHERM ® Device Treatment HIFUHYPERTHERMIA l High Temperature (>85 °C) l Short Time (< 5 Sec.) l Low Temperature (< 45 °C) l Long Duration (>1 Hr) Time Temp. Two different approaches to reach the destruction threshold : Temp. Time Local Increase of Tissue Temperature BPH CANCER Physical Principle Treatment Description

18 HIFU Technology History ABLATHERM ® Device Treatment Transducer Positioning Treatment Description Physical Principle Precise lesion positioning with dynamic focusing Sparing of surrounding tissue

19 HIFU Technology History ABLATHERM ® Device Treatment Lesion Distribution within the Prostate Each shot consists of a burst of ultrasound waves with a duration of 5 seconds The focal volume is very small: 19-24 mm in length by 1.7 mm in diameter Treatment Description Physical Principle

20 HIFU Technology History ABLATHERM ® Device Treatment Lesion Distribution within the Prostate Treatment Description Physical Principle

21 HIFU Technology History ABLATHERM ® Device Treatment The firing head moves until the whole targeted volume is treated Lesion Distribution within the Prostate Treatment Description Physical Principle

22 HIFU Technology History ABLATHERM ® Device Treatment History of the Ablatherm® Project 1989: Preliminary experiments on rats kidneys and technology development 1990: Cancer treatment - feasibility: Dunning tumors 1991: Endorectal approach - feasibility: canine prostate 1993: Treatment efficacy - evaluation: PCa 1995: Device safety improvements 1996: European Multicentric Study 2000: Mark Ablatherm ® Maxis 2005: Mark Ablatherm ® Integrated Imaging

23 HIFU Technology History ABLATHERM ® Device Treatment CE Mark Ablatherm® Marked January 2000

24 HIFU Technology History ABLATHERM ® Device Treatment In excess 9000 treatments in 100 sites in Europe Patients treated with Ablatherm every year 1000 2000

25 HIFU Technology History ABLATHERM ® Device Treatment Ablatherm® HIFU

26 HIFU Technology History ABLATHERM ® Device Treatment Device Description RF Power Imaging and Firing System Electronics and safeties + Disposable Endorectal Probe Cooling Motors User Interface Command Module Treatment Module Probe Module Patient Support Computer Probe General Description

27 HIFU Technology History ABLATHERM ® Device Treatment 2 functions, 2 transducers integrated in ONE probe Imaging Treatment Endorectal Probe Real-time ultrasound imaging. 7.5 MHz high-definition image. Electronic array technology. A 3 MHz transducer. Dynamic positioning with respect to rectal wall. Wide opening. ProbeGeneral Description

28 HIFU Technology History ABLATHERM ® Device Treatment Integrated imaging 2 different transducers with an Integrated imaging 7.5 MHz probe High resolution imaging system ProbeGeneral Description

29 HIFU Technology History ABLATHERM ® Device Treatment Imaging & Treating Simultaneously From a transversal real-time image, the 7.5 MHz electronic ultrasound transducer can provide an accurate 3D reconstruction of the treatment area. Imaging Firing High-energy ultrasound waves are focused through the rectal wall to the targeted prostate area. ProbeGeneral Description

30 HIFU Technology History ABLATHERM ® Device Treatment Indications Positioning Treatment Summary Candidate for RPP EBRT failure Recurrence after previous HIFU

31 HIFU Technology History ABLATHERM ® Device Treatment Main Steps of a Treatment Probe preparation (Ablapak ® disposable) Patient installation (Immobilization) Prostate localization (Apex identification) - Longitudinal imaging - Transversal imaging Treatment (Safety controls) Patient removal Probe cleaning and disinfection Positioning Treatment Summary

32 HIFU Technology History ABLATHERM ® Device Treatment Patient Installation (Immobilization) Patient positioned in right lateral decubitus position Positioning Treatment Summary

33 HIFU Technology History ABLATHERM ® Device Treatment Patient Installation (Immobilization) Patient movement detector Positioning Treatment Summary

34 HIFU Technology History ABLATHERM ® Device Treatment Probe insertion Intra-rectal positioning Prostate localization (1) Positioning Treatment Summary

35 HIFU Technology History ABLATHERM ® Device Treatment Prostate localization (2) Probe insertion Robotized movements Positioning Treatment Summary If the video doesn’t start automatically click on the window

36 HIFU Technology History ABLATHERM ® Device Treatment Prostate localization (3) Automatic imaging phase 3D reconstruction Positioning Treatment Summary

37 HIFU Technology History ABLATHERM ® Device Treatment Prostate localization (4) Automatic imaging phase 3D reconstruction Positioning Treatment Summary If the video doesn’t start automatically click on the window

38 HIFU Technology History ABLATHERM ® Device Treatment Treatment (planning) Positioning Treatment Summary Treatment area programming Firing phase

39 HIFU Technology History ABLATHERM ® Device Treatment Treatment (planning) Positioning Treatment Summary Treatment area programming Firing phase

40 HIFU Technology History ABLATHERM ® Device Treatment Treatment (planning) Positioning Treatment Summary Treatment area programmingFiring phase If the video doesn’t start automatically click on the window

41 HIFU Technology History ABLATHERM ® Device Treatment Treatment (planning) Positioning Treatment Summary Treatment area programmingFiring phase If the video doesn’t start automatically click on the window

42 HIFU Technology History ABLATHERM ® Device Treatment Treatment (Safety Controls) Main safety features Power / Firing sequence Probe position Patient movement Rectum position Temperature Positioning Treatment Summary Exit

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