1. Modifications in ACAP © Created by Isaac P. E. Mailleue Research Integrity Coordinator University of North Carolina at Greensboro September 2013

2. Modifications in ACAP No one is perfect. If you make a spelling error or are asked by the Vet to change a procedure after submitting to ACAP but before you have been approved, you will need to make modifications.

3. Once you have submitted your protocol to on ACAP, comments will be made by several groups, including the Vet, IACUC, and the Office of Research Integrity (ORI).

4. ACAP developers and the ORI recommend you use Internet Explorer when using ACAP. Some bugs have been much more likely to occur with other browsers. We also recommend you always click buttons instead of hitting the “Enter” key. Again, some bugs seem more frequent if you hit the “Enter” key

5. Log into ACAP If you have been instructed to modify your protocol before receiving IACUC approval, click “In Process”.

6. Now click on the study you have been asked to modify.

7. If you have issues to address, the top of the page will have an “Attention Required” message

8. Pay attention to the checks and speech bubbles

9. A “speech bubble” indicates comment boxes. If there is a green circle with a plus, there are no comments for that section. If the “speech bubble” does not have a green circle, a comment has been made on this section of your protocol.

10. Click on a speech bubble without a green circle to see the comment.

11. Go into the appropriate section of your protocol and make the requested changes.

12. If you would like, type any response you have in the lower text box, then click “Submit Response”. Please note that if you choose to respond in the comment box, you will still need to make the requested changes

13. Once you have addressed the comments, your protocol will not have the “Attention Required” text in red. (“Attention Required” would appear where the blue arrow is pointing) If you have addressed all comments and do not see “Attention Required” submit your application.

14. Congratulations! You have made modifications in ACAP!